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Association of intraindividual tacrolimus variability with de novo donor-specific HLA antibody development and allograft rejection in pediatric kidney transplant recipients with low immunological risk

Tacrolimus (Tac) intraindividual variability (TacIPV) in pediatric kidney transplant patients is only poorly understood. We investigated the impact of TacIPV on de novo donor-specific HLA antibodies (dnDSA) development and allograft rejection in Caucasian pediatric recipients of a living or deceased...

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Main Authors: Baghai Arassi, Maral (Author) , Gauche, Laura (Author) , Schmidt, Jeremy (Author) , Höcker, Britta (Author) , Rieger, Susanne (Author) , Süsal, Caner (Author) , Tönshoff, Burkhard (Author) , Fichtner, Alexander (Author)
Format: Article (Journal)
Language:English
Published: 15 February 2022
In: Pediatric nephrology
Year: 2022, Volume: 37, Issue: 10, Pages: 2503-2514
ISSN:1432-198X
DOI:10.1007/s00467-022-05426-3
Online Access:Resolving-System, kostenfrei, Volltext: https://doi.org/10.1007/s00467-022-05426-3
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Author Notes:Maral Baghai Arassi, Laura Gauche, Jeremy Schmidt, Britta Höcker, Susanne Rieger, Caner Süsal, Burkhard Tönshoff, Alexander Fichtner
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Summary:Tacrolimus (Tac) intraindividual variability (TacIPV) in pediatric kidney transplant patients is only poorly understood. We investigated the impact of TacIPV on de novo donor-specific HLA antibodies (dnDSA) development and allograft rejection in Caucasian pediatric recipients of a living or deceased donor kidney with low immunological risk.
Item Description:Gesehen am 07.03.2023
Physical Description:Online Resource
ISSN:1432-198X
DOI:10.1007/s00467-022-05426-3

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