A boundary delimitation algorithm to approximate cell soma volumes of bipolar cells from topographical data obtained by scanning probe microscopy

Cell volume determination plays a pivotal role in the investigation of the biophysical mechanisms underlying various cellular processes. Whereas light microscopy in principle enables one to obtain three dimensional data, the reconstruction of cell volume from z-stacks is a time consuming procedure....

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Bibliographic Details
Main Authors: Happel, Patrick (Author) , Möller, Kerstin (Author) , Kunz, Ralf (Author) , Dietzel, Irmgard D. (Author)
Format: Article (Journal)
Language:English
Published: 15 June 2010
In: BMC bioinformatics
Year: 2010, Volume: 11, Pages: 1-16
ISSN:1471-2105
DOI:10.1186/1471-2105-11-323
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/1471-2105-11-323
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Author Notes:Patrick Happel, Kerstin Möller, Ralf Kunz and Irmgard D. Dietzel
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Summary:Cell volume determination plays a pivotal role in the investigation of the biophysical mechanisms underlying various cellular processes. Whereas light microscopy in principle enables one to obtain three dimensional data, the reconstruction of cell volume from z-stacks is a time consuming procedure. Thus, three dimensional topographic representations of cells are easier to obtain by scanning probe microscopical measurements.
Item Description:Gesehen am 08.03.2023
Physical Description:Online Resource
ISSN:1471-2105
DOI:10.1186/1471-2105-11-323