“Groove and peel” deep anterior lamellar keratoplasty: how deep can you go?

Purpose: - The aim of the current research was to measure the thickness of the residual central corneal bed after performing the manual “Groove and Peel” deep anterior lamellar keratoplasty (GP-DALK) technique on human cadaveric eyes. - Methods: - The manual GP-DALK technique was performed on...

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Main Authors: Son, Hyeck Soo (Author) , Rigi, Mohammed (Author) , Srikumaran, Divya (Author) , Eberhart, Charles G. (Author) , Jun, Albert S. (Author) , Soiberman, Uri S. (Author)
Format: Article (Journal)
Language:English
Published: January 2023
In: Cornea
Year: 2023, Volume: 42, Issue: 1, Pages: 105-109
ISSN:1536-4798
DOI:10.1097/ICO.0000000000003103
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1097/ICO.0000000000003103
Verlag, lizenzpflichtig, Volltext: https://journals.lww.com/corneajrnl/Abstract/2023/01000/_Groove_and_Peel__Deep_Anterior_Lamellar.15.aspx
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Author Notes:Hyeck-Soo Son, Mohammed Rigi, Divya Srikumaran, Charles G. Eberhart, Albert S. Jun, Uri S. Soiberman
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Summary:Purpose: - The aim of the current research was to measure the thickness of the residual central corneal bed after performing the manual “Groove and Peel” deep anterior lamellar keratoplasty (GP-DALK) technique on human cadaveric eyes. - Methods: - The manual GP-DALK technique was performed on 6 human cadaver eyes by an experienced corneal surgeon. After surgery, the eye globes were fixed in 10% buffered formalin and embedded in paraffin. For each eye, 4-μm-thick hematoxylin and eosin sections involving the pupillary axis were obtained and examined. Using an image-processing software, 2 observers measured the corneal thickness of the residual central corneal bed and the peripheral corneal rims. - Results: - The overall mean central corneal bed thickness was 35.5 ± 12.9 μm, whereas the mean right and left peripheral rim thicknesses were 993.0 ± 141.1 and 989.3 ± 147.1 μm, respectively (P = 0.0006). In most corneas, the level of dissection reached almost to the pre-Descemetic collagen (Dua) layer. - Conclusions: - The GP-DALK technique is effective in removing most of the corneal stroma and may be non-inferior to “big-bubble” deep anterior lamellar keratoplasty in some cases.
Item Description:Gesehen am 15.03.2023
Physical Description:Online Resource
ISSN:1536-4798
DOI:10.1097/ICO.0000000000003103