“Groove and peel” deep anterior lamellar keratoplasty: how deep can you go?

Purpose: - The aim of the current research was to measure the thickness of the residual central corneal bed after performing the manual “Groove and Peel” deep anterior lamellar keratoplasty (GP-DALK) technique on human cadaveric eyes. - Methods: - The manual GP-DALK technique was performed on...

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Hauptverfasser: Son, Hyeck Soo (Verfasst von) , Rigi, Mohammed (Verfasst von) , Srikumaran, Divya (Verfasst von) , Eberhart, Charles G. (Verfasst von) , Jun, Albert S. (Verfasst von) , Soiberman, Uri S. (Verfasst von)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: January 2023
In: Cornea
Year: 2023, Jahrgang: 42, Heft: 1, Pages: 105-109
ISSN:1536-4798
DOI:10.1097/ICO.0000000000003103
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1097/ICO.0000000000003103
Verlag, lizenzpflichtig, Volltext: https://journals.lww.com/corneajrnl/Abstract/2023/01000/_Groove_and_Peel__Deep_Anterior_Lamellar.15.aspx
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Verfasserangaben:Hyeck-Soo Son, Mohammed Rigi, Divya Srikumaran, Charles G. Eberhart, Albert S. Jun, Uri S. Soiberman
Beschreibung
Zusammenfassung:Purpose: - The aim of the current research was to measure the thickness of the residual central corneal bed after performing the manual “Groove and Peel” deep anterior lamellar keratoplasty (GP-DALK) technique on human cadaveric eyes. - Methods: - The manual GP-DALK technique was performed on 6 human cadaver eyes by an experienced corneal surgeon. After surgery, the eye globes were fixed in 10% buffered formalin and embedded in paraffin. For each eye, 4-μm-thick hematoxylin and eosin sections involving the pupillary axis were obtained and examined. Using an image-processing software, 2 observers measured the corneal thickness of the residual central corneal bed and the peripheral corneal rims. - Results: - The overall mean central corneal bed thickness was 35.5 ± 12.9 μm, whereas the mean right and left peripheral rim thicknesses were 993.0 ± 141.1 and 989.3 ± 147.1 μm, respectively (P = 0.0006). In most corneas, the level of dissection reached almost to the pre-Descemetic collagen (Dua) layer. - Conclusions: - The GP-DALK technique is effective in removing most of the corneal stroma and may be non-inferior to “big-bubble” deep anterior lamellar keratoplasty in some cases.
Beschreibung:Gesehen am 15.03.2023
Beschreibung:Online Resource
ISSN:1536-4798
DOI:10.1097/ICO.0000000000003103