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Intraindividual comparison of selective arterial versus venous 68Ga-DOTATOC PET/CT in patients with gastroenteropancreatic neuroendocrine tumors

Therapy with the somatostatin analogue DOTA-(0)-Phe(1)-Tyr(3)-octreotide (DOTATOC) labeled with a β-(DOTA-Phe-Tyr-Octreotide) emitter such as 90Y or 177Lu is accepted for the palliative treatment of unresectable neuroendocrine cancer. However, the optimal route of administration has not been determi...

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Main Authors: Kratochwil, Clemens (Author) , Giesel, Frederik L. (Author) , López-Benítez, Ruben (Author) , Schimpfky, Nadine (Author) , Kunze, Kirsten (Author) , Eisenhut, Michael (Author) , Kauczor, Hans-Ulrich (Author) , Haberkorn, Uwe (Author)
Format: Article (Journal)
Language:English
Published: 05/11/2010
In: Clinical cancer research
Year: 2010, Volume: 16, Issue: 10, Pages: 2899-2905
ISSN:1557-3265
DOI:10.1158/1078-0432.CCR-10-0004
Online Access:Resolving-System, kostenfrei, Volltext: https://doi.org/10.1158/1078-0432.CCR-10-0004
Resolving-System, kostenfrei, Volltext: https://aacrjournals.org/clincancerres/article/16/10/2899/75199/Intraindividual-Comparison-of-Selective-Arterial
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Author Notes:Clemens Kratochwil, Frederik L. Giesel, Ruben López-Benítez, Nadine Schimpfky, Kirsten Kunze, Michael Eisenhut, Hans-Ulrich Kauczor, and Uwe Haberkorn
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Summary:Therapy with the somatostatin analogue DOTA-(0)-Phe(1)-Tyr(3)-octreotide (DOTATOC) labeled with a β-(DOTA-Phe-Tyr-Octreotide) emitter such as 90Y or 177Lu is accepted for the palliative treatment of unresectable neuroendocrine cancer. However, the optimal route of administration has not been determined. Using positron-emission tomography (PET)-labeled 68Ga-DOTATOC, we compared selective tumoral uptake on PET/computed tomography (CT) after arterial or venous administration of the agent in patients with gastroenteropancreatic neuroendocrine tumor.
Item Description:Gesehen am 23.03.2023
Physical Description:Online Resource
ISSN:1557-3265
DOI:10.1158/1078-0432.CCR-10-0004

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