Effectiveness of a community intervention on malaria in rural Tanzania: a randomised controlled trial

Background - Malaria infections are a major public health problem in Africa and prompt treatment is one way of controlling the disease and saving lives. - Methods - This cluster-randomised controlled community intervention conducted in 2003-2005 aimed at improving early malaria case management in un...

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Main Authors: Eriksen, Jaran (Author) , Mujinja, P (Author) , Warsame, M (Author) , Nsimba, S (Author) , Kouyaté, B (Author) , Gustafsson, LL (Author) , Jahn, Albrecht (Author) , Müller, Olaf (Author) , Sauerborn, Rainer (Author) , Tomson, G (Author)
Format: Article (Journal)
Language:English
Published: December 2010
In: African health sciences
Year: 2010, Volume: 10, Issue: 4, Pages: 332-340
ISSN:1729-0503
Online Access:Verlag, lizenzpflichtig, Volltext: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3052812/
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Author Notes:Eriksen J, Mujinja P, Warsame M, Nsimba S, Kouyaté B, Gustafsson LL, Jahn A, Müller O, Sauerborn R, Tomson G
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Summary:Background - Malaria infections are a major public health problem in Africa and prompt treatment is one way of controlling the disease and saving lives. - Methods - This cluster-randomised controlled community intervention conducted in 2003-2005 aimed at improving early malaria case management in under five children. Health workers were trained to train community-based women groups in recognizing malaria symptoms, providing first-line treatment for uncomplicated malaria and referring severe cases. Evaluation was through a pre- (2004) and a post-intervention survey (2005). Anaemia prevalence was the primary outcome. - Results - 1715 children aged 6-59 months were included in the pre-intervention survey and 2169 in the post-intervention survey. The prevalence of anaemia decreased significantly from 37% [95% CI 34.7-39.3] to 0.5% [95% CI 0.2-0.7] after the intervention (p<0.001); slightly more in the intervention (from 43.9% to 0.8%) than in the control (30.8% to 0.17%) group (p=0.038). Fever and reported fever decreased significantly and the mean body weight of the children increased significantly over the study period in both control and intervention groups. - Conclusion - The decrease in anaemia was significantly associated with the intervention, whereas the fever and body weight trends might be explained by other malaria control activities or seasonal/climate effects in the area. The community intervention was shown to be feasible in the study context.
Item Description:Gesehen am 27.03.2023
Physical Description:Online Resource
ISSN:1729-0503