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Novel FAP ligands enable improved imaging contrast in sarcoma patients due to FAPI-PET/CT

A high expression of fibroblast activation protein (FAP) was observed in multiple sarcomas, indicating an enormous potential for PET/CT using 68Ga-radiolabeled inhibitors of FAP (FAPI). Therefore, this retrospective study aimed to evaluate the role of the novel hybrid imaging probe for sarcomas as a...

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Main Authors: Körber, Stefan A. (Author) , Finck, Rebecca (Author) , Dendl, Katharina (Author) , Uhl, Matthias (Author) , Lindner, Thomas (Author) , Kratochwil, Clemens (Author) , Röhrich, Manuel (Author) , Rathke, Hendrik (Author) , Ungerechts, Guy (Author) , Adeberg, Sebastian (Author) , Herfarth, Klaus (Author) , Jäger, Dirk (Author) , Debus, Jürgen (Author) , Haberkorn, Uwe (Author) , Giesel, Frederik L. (Author)
Format: Article (Journal)
Language:English
Published: 21 May 2021
In: European journal of nuclear medicine and molecular imaging
Year: 2021, Volume: 48, Issue: 12, Pages: 3918-3924
ISSN:1619-7089
DOI:10.1007/s00259-021-05374-4
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1007/s00259-021-05374-4
Verlag, kostenfrei, Volltext: https://link.springer.com/article/10.1007/s00259-021-05374-4
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Author Notes:Stefan A. Koerber, R. Finck, K. Dendl, M. Uhl, T. Lindner, C. Kratochwil, M. Röhrich, H. Rathke, G. Ungerechts, S. Adeberg, K. Herfarth, D. Jaeger, J. Debus, U. Haberkorn, F.L. Giesel
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Summary:A high expression of fibroblast activation protein (FAP) was observed in multiple sarcomas, indicating an enormous potential for PET/CT using 68Ga-radiolabeled inhibitors of FAP (FAPI). Therefore, this retrospective study aimed to evaluate the role of the novel hybrid imaging probe for sarcomas as a first clinical evaluation.
Item Description:Gesehen am 29.03.2023
Physical Description:Online Resource
ISSN:1619-7089
DOI:10.1007/s00259-021-05374-4

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