Design, synthesis and biological evaluation of simplified analogues of the RNA polymerase inhibitor etnangien
Novel simplified analogues of the potent RNA polymerase inhibitor etnangien were obtained by total synthesis and evaluated for antibacterial activity against Gram-positive bacteria and one Gram-negative bacterium.
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| Main Authors: | , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
2010
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| In: |
Bioorganic & medicinal chemistry letters
Year: 2010, Volume: 20, Issue: 3, Pages: 939-941 |
| ISSN: | 1464-3405 |
| DOI: | 10.1016/j.bmcl.2009.12.066 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.bmcl.2009.12.066 Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S0960894X09017892 
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| Author Notes: | Dirk Menche, Pengfei Li, Herbert Irschik |
| Summary: | Novel simplified analogues of the potent RNA polymerase inhibitor etnangien were obtained by total synthesis and evaluated for antibacterial activity against Gram-positive bacteria and one Gram-negative bacterium. |
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| Item Description: | Erstmals am 23. Dezember 2009 online erschienen Gesehen am 13.04.2023 |
| Physical Description: | Online Resource |
| ISSN: | 1464-3405 |
| DOI: | 10.1016/j.bmcl.2009.12.066 |