Effects of the main green tea polyphenol epigallocatechin-3-gallate on cardiac involvement in patients with AL amyloidosis

Amyloid light chain (AL) amyloidosis is a rare disease with poor prognosis and limited therapeutic alternatives. Recently, one clinical case with cardiac involvement, as well as a compelling evidence of green tea polyphenol, epigallocatechin-3-gallate (EGCG), inducing the formation of benign aggrega...

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Main Authors: Mereles, Derliz (Author) , Buß, Sebastian Johannes (Author) , Hardt, Stefan (Author) , Hunstein, Werner (Author) , Katus, Hugo (Author)
Format: Article (Journal)
Language:English
Published: 10 March 2010
In: Clinical research in cardiology
Year: 2010, Volume: 99, Issue: 8, Pages: 483-490
ISSN:1861-0692
DOI:10.1007/s00392-010-0142-x
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1007/s00392-010-0142-x
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Author Notes:Derliz Mereles, Sebastian J. Buss, Stefan E. Hardt, Werner Hunstein, Hugo A. Katus
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Summary:Amyloid light chain (AL) amyloidosis is a rare disease with poor prognosis and limited therapeutic alternatives. Recently, one clinical case with cardiac involvement, as well as a compelling evidence of green tea polyphenol, epigallocatechin-3-gallate (EGCG), inducing the formation of benign aggregation products that do not polymerize into fibrils were published. This is a report of the cardiac effects of green tea consumption in these patients.
Item Description:Gesehen am 19.04.2023
Physical Description:Online Resource
ISSN:1861-0692
DOI:10.1007/s00392-010-0142-x