Rationale and design of the FreezeAF trial: a randomized controlled noninferiority trial comparing isolation of the pulmonary veins with the cryoballoon catheter versus open irrigated radiofrequency ablation in patients with paroxysmal atrial fibrillation
Atrial fibrillation is the most commonly encountered clinical arrhythmia, and there are an increasing number of patients with paroxysmal atrial fibrillation treated by catheter ablation. The criterion standard is the isolation of the pulmonary veins (PVs) using radiofrequency (RF) energy in combinat...
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| Main Authors: | , , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
1 April 2010
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| In: |
American heart journal
Year: 2010, Volume: 159, Issue: 4, Pages: 555-560.e1 |
| ISSN: | 1097-6744 |
| DOI: | 10.1016/j.ahj.2010.01.008 |
| Online Access: | Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.ahj.2010.01.008 Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S0002870310000797 
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| Author Notes: | Armin Luik, Matthias Merkel, Danielle Hoeren, Tobias Riexinger, Meinhard Kieser, and Claus Schmitt |
| Summary: | Atrial fibrillation is the most commonly encountered clinical arrhythmia, and there are an increasing number of patients with paroxysmal atrial fibrillation treated by catheter ablation. The criterion standard is the isolation of the pulmonary veins (PVs) using radiofrequency (RF) energy in combination with an open irrigated tip catheter. The procedure remains technically challenging with a significant number of complications. So far, no randomized comparisons between the outcome of cryoballoon versus RF ablation are available. |
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| Item Description: | Gesehen am 19.04.2023 |
| Physical Description: | Online Resource |
| ISSN: | 1097-6744 |
| DOI: | 10.1016/j.ahj.2010.01.008 |