Cover Image

Interleukin-3 protects against viral pneumonia in sepsis by enhancing plasmacytoid dendritic cell recruitment into the lungs and T cell priming

Sepsis, a global health burden, is often complicated by viral infections leading to increased long-term morbidity and mortality. Interleukin-3 (IL-3) has been identified as an important mediator amplifying acute inflammation in sepsis; however, its function in the host response to viral infections d...

Full description

Saved in:
Bibliographic Details
Main Authors: Bénard, Alan (Author) , Hansen, Frederik J. (Author) , Uhle, Florian (Author) , Klösch, Bettina (Author) , Czubayko, Franziska (Author) , Mittelstädt, Anke (Author) , Jacobsen, Anne (Author) , David, Paul (Author) , Podolska, Malgorzata Justyna (Author) , Anthuber, Anna (Author) , Swierzy, Izabela (Author) , Schaack, Dominik (Author) , Mühl-Zürbes, Petra (Author) , Steinkasserer, Alexander (Author) , Weyand, Michael (Author) , Weigand, Markus A. (Author) , Brenner, Thorsten (Author) , Krautz, Christian (Author) , Grützmann, Robert (Author) , Weber, Georg Ferdinand (Author)
Format: Article (Journal)
Language:English
Published: 22 February 2023
In: Frontiers in immunology
Year: 2023, Volume: 14, Pages: 1-12
ISSN:1664-3224
DOI:10.3389/fimmu.2023.1140630
Online Access:Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.3389/fimmu.2023.1140630
Verlag, lizenzpflichtig, Volltext: https://www.frontiersin.org/articles/10.3389/fimmu.2023.1140630
Get full text
Author Notes:Alan Bénard, Frederik J. Hansen, Florian Uhle, Bettina Klösch, Franziska Czubayko, Anke Mittelstädt, Anne Jacobsen, Paul David, Malgorzata J. Podolska, Anna Anthuber, Izabela Swierzy, Dominik Schaack, Petra Mühl-Zürbes, Alexander Steinkasserer, Michael Weyand, Markus A. Weigand, Thorsten Brenner, Christian Krautz, Robert Grützmann and Georg F. Weber
Description
Summary:Sepsis, a global health burden, is often complicated by viral infections leading to increased long-term morbidity and mortality. Interleukin-3 (IL-3) has been identified as an important mediator amplifying acute inflammation in sepsis; however, its function in the host response to viral infections during sepsis remains elusive. To investigate the role of IL-3 during viral pneumonia in sepsis.
Item Description:Gesehen am 21.11.2023
Physical Description:Online Resource
ISSN:1664-3224
DOI:10.3389/fimmu.2023.1140630

Similar Items