Interleukin-3 protects against viral pneumonia in sepsis by enhancing plasmacytoid dendritic cell recruitment into the lungs and T cell priming
Sepsis, a global health burden, is often complicated by viral infections leading to increased long-term morbidity and mortality. Interleukin-3 (IL-3) has been identified as an important mediator amplifying acute inflammation in sepsis; however, its function in the host response to viral infections d...
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| Main Authors: | , , , , , , , , , , , , , , , , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
22 February 2023
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| In: |
Frontiers in immunology
Year: 2023, Volume: 14, Pages: 1-12 |
| ISSN: | 1664-3224 |
| DOI: | 10.3389/fimmu.2023.1140630 |
| Online Access: | Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.3389/fimmu.2023.1140630 Verlag, lizenzpflichtig, Volltext: https://www.frontiersin.org/articles/10.3389/fimmu.2023.1140630 
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| Author Notes: | Alan Bénard, Frederik J. Hansen, Florian Uhle, Bettina Klösch, Franziska Czubayko, Anke Mittelstädt, Anne Jacobsen, Paul David, Malgorzata J. Podolska, Anna Anthuber, Izabela Swierzy, Dominik Schaack, Petra Mühl-Zürbes, Alexander Steinkasserer, Michael Weyand, Markus A. Weigand, Thorsten Brenner, Christian Krautz, Robert Grützmann and Georg F. Weber |
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| 520 | |a Sepsis, a global health burden, is often complicated by viral infections leading to increased long-term morbidity and mortality. Interleukin-3 (IL-3) has been identified as an important mediator amplifying acute inflammation in sepsis; however, its function in the host response to viral infections during sepsis remains elusive. To investigate the role of IL-3 during viral pneumonia in sepsis. | ||
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