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18F FDG PET/MRI with hepatocyte-specific contrast agent for M staging of rectal cancer: a primary economic evaluation

Rectal cancer is one of the most frequent causes of cancer-related morbidity and mortality in the world. Correct identification of the TNM state in primary staging of rectal cancer has critical implications on patient management. Initial evaluations revealed a high sensitivity and specificity for wh...

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Hauptverfasser: Gassert, Felix (VerfasserIn) , Rübenthaler, Johannes (VerfasserIn) , Cyran, Clemens C. (VerfasserIn) , Rink, Johann (VerfasserIn) , Schwarze, Vincent (VerfasserIn) , Luitjens, Johanna (VerfasserIn) , Gassert, Florian T. (VerfasserIn) , Makowski, Marcus R. (VerfasserIn) , Schönberg, Stefan (VerfasserIn) , Mayerhoefer, Marius E. (VerfasserIn) , Tamandl, Dietmar (VerfasserIn) , Froelich, Matthias F. (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 09 March 2021
In: European journal of nuclear medicine and molecular imaging
Year: 2021, Jahrgang: 48, Heft: 10, Pages: 3268-3276
ISSN:1619-7089
DOI:10.1007/s00259-021-05193-7
Online-Zugang:Verlag, kostenfrei, Volltext: https://doi.org/10.1007/s00259-021-05193-7
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Verfasserangaben:Felix G. Gassert, Johannes Rübenthaler, Clemens C. Cyran, Johann S. Rink, Vincent Schwarze, Johanna Luitjens, Florian T. Gassert, Marcus R. Makowski, Stefan O. Schoenberg, Marius E. Mayerhoefer, Dietmar Tamandl, Matthias F. Froelich
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Zusammenfassung:Rectal cancer is one of the most frequent causes of cancer-related morbidity and mortality in the world. Correct identification of the TNM state in primary staging of rectal cancer has critical implications on patient management. Initial evaluations revealed a high sensitivity and specificity for whole-body PET/MRI in the detection of metastases allowing for metastasis-directed therapy regimens. Nevertheless, its cost-effectiveness compared with that of standard-of-care imaging (SCI) using pelvic MRI + chest and abdominopelvic CT is yet to be investigated. Therefore, the aim of this study was to analyze the cost-effectiveness of whole-body 18F FDG PET/MRI as an alternative imaging method to standard diagnostic workup for initial staging of rectal cancer.
Beschreibung:Im Titel ist "18" hochgestellt
Gesehen am 27.04.2023
Beschreibung:Online Resource
ISSN:1619-7089
DOI:10.1007/s00259-021-05193-7

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