Buchumschlag

Cluster protocols in SCIT: enough evidence for practical use?

Purpose of review - The review provides a comprehensive evaluation of Cluster schedules in subcutaneous-specific immunotherapy (SCIT) in terms of the safety profile and onset of clinical and immunological effects. - Recent findings - Recent major clinical studies could clearly reveal that Clu...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Pfaar, Oliver (VerfasserIn) , Leitzbach, Sarah (VerfasserIn) , Hörmann, Karl (VerfasserIn) , Klimek, Ludger (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: June 2010
In: Current opinion in allergy and clinical immunology
Year: 2010, Jahrgang: 10, Heft: 3, Pages: 1-6
ISSN:1473-6322
DOI:10.1097/ACI.0b013e328339505c
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1097/ACI.0b013e328339505c
Verlag, lizenzpflichtig, Volltext: https://journals.lww.com/co-allergy/Fulltext/2010/06000/Cluster_protocols_in_SCIT__enough_evidence_for.7.aspx
Volltext
Verfasserangaben:Oliver Pfaar, Sarah Leitzbach, Karl Hörmann and Ludger Klimek

MARC

LEADER 00000caa a2200000 c 4500
001 1843801094
003 DE-627
005 20240327080246.0
007 cr uuu---uuuuu
008 230428s2010 xx |||||o 00| ||eng c
024 7 |a 10.1097/ACI.0b013e328339505c  |2 doi 
035 |a (DE-627)1843801094 
035 |a (DE-599)KXP1843801094 
035 |a (OCoLC)1389806207 
040 |a DE-627  |b ger  |c DE-627  |e rda 
041 |a eng 
084 |a 33  |2 sdnb 
100 1 |a Pfaar, Oliver  |d 1972-  |e VerfasserIn  |0 (DE-588)12385900X  |0 (DE-627)706454049  |0 (DE-576)293913099  |4 aut 
245 1 0 |a Cluster protocols in SCIT  |b enough evidence for practical use?  |c Oliver Pfaar, Sarah Leitzbach, Karl Hörmann and Ludger Klimek 
264 1 |c June 2010 
300 |a 6 
336 |a Text  |b txt  |2 rdacontent 
337 |a Computermedien  |b c  |2 rdamedia 
338 |a Online-Ressource  |b cr  |2 rdacarrier 
500 |a Gesehen am 28.03.2023 
520 |a Purpose of review - The review provides a comprehensive evaluation of Cluster schedules in subcutaneous-specific immunotherapy (SCIT) in terms of the safety profile and onset of clinical and immunological effects. - Recent findings - Recent major clinical studies could clearly reveal that Cluster schedules with both (semi-)depot-allergen preparations and chemically modified allergen preparations (‘allergoids’) are well tolerated therapeutic options in SCIT comparable to the safety profile of conventional build-up schedules. Moreover, preliminary data indicate that these accelerated protocols result in a more rapid achievement of clinical and immunological effects. - Summary - Conventional schedules in SCIT have the disadvantage of both a high expenditure of time and the need for a high patient compliance. In accelerated cluster schedules two to three injections are administered sequentially per treatment day (with an interval of 30 min between the injections) in weekly intervals aimed to reach the maintenance dose of SCIT in a short time interval. Recent studies indicate that these accelerated SCIT protocols result in a more rapid achievement of clinical and immunological effects than conventional schedules. Moreover, the safety profile is comparable between conventional and cluster SCIT. 
700 1 |a Leitzbach, Sarah  |d 1982-  |e VerfasserIn  |0 (DE-588)138967547  |0 (DE-627)703166883  |0 (DE-576)309050103  |4 aut 
700 1 |a Hörmann, Karl  |d 1948-  |e VerfasserIn  |0 (DE-588)130123749  |0 (DE-627)49171193X  |0 (DE-576)266607438  |4 aut 
700 1 |a Klimek, Ludger  |d 1964-  |e VerfasserIn  |0 (DE-588)172705037  |0 (DE-627)697637476  |0 (DE-576)133562751  |4 aut 
773 0 8 |i Enthalten in  |t Current opinion in allergy and clinical immunology  |d London : Lippincott Williams & Wilkins, 2001  |g 10(2010), 3 vom: Juni, Artikel-ID 188, Seite 1-6  |h Online-Ressource  |w (DE-627)325699453  |w (DE-600)2039287-4  |w (DE-576)103189513  |x 1473-6322  |7 nnas  |a Cluster protocols in SCIT enough evidence for practical use? 
773 1 8 |g volume:10  |g year:2010  |g number:3  |g month:06  |g elocationid:188  |g pages:1-6  |g extent:6  |a Cluster protocols in SCIT enough evidence for practical use? 
856 4 0 |u https://doi.org/10.1097/ACI.0b013e328339505c  |x Verlag  |x Resolving-System  |z lizenzpflichtig  |3 Volltext 
856 4 0 |u https://journals.lww.com/co-allergy/Fulltext/2010/06000/Cluster_protocols_in_SCIT__enough_evidence_for.7.aspx  |x Verlag  |z lizenzpflichtig  |3 Volltext 
951 |a AR 
992 |a 20230428 
993 |a Article 
994 |a 2010 
998 |g 172705037  |a Klimek, Ludger  |m 172705037:Klimek, Ludger  |d 60000  |e 60000PK172705037  |k 0/60000/  |p 4  |y j 
998 |g 130123749  |a Hörmann, Karl  |m 130123749:Hörmann, Karl  |d 60000  |d 62100  |d 60000  |e 60000PH130123749  |e 62100PH130123749  |e 60000PH130123749  |k 0/60000/  |k 1/60000/62100/  |k 0/60000/  |p 3 
998 |g 138967547  |a Leitzbach, Sarah  |m 138967547:Leitzbach, Sarah  |d 60000  |d 62100  |e 60000PL138967547  |e 62100PL138967547  |k 0/60000/  |k 1/60000/62100/  |p 2 
998 |g 12385900X  |a Pfaar, Oliver  |m 12385900X:Pfaar, Oliver  |d 60000  |d 62100  |d 60000  |e 60000PP12385900X  |e 62100PP12385900X  |e 60000PP12385900X  |k 0/60000/  |k 1/60000/62100/  |k 0/60000/  |p 1  |x j 
999 |a KXP-PPN1843801094  |e 4316015478 
BIB |a Y 
SER |a journal 
JSO |a {"recId":"1843801094","language":["eng"],"note":["Gesehen am 28.03.2023"],"type":{"media":"Online-Ressource","bibl":"article-journal"},"person":[{"role":"aut","display":"Pfaar, Oliver","roleDisplay":"VerfasserIn","given":"Oliver","family":"Pfaar"},{"role":"aut","display":"Leitzbach, Sarah","roleDisplay":"VerfasserIn","given":"Sarah","family":"Leitzbach"},{"role":"aut","roleDisplay":"VerfasserIn","display":"Hörmann, Karl","given":"Karl","family":"Hörmann"},{"display":"Klimek, Ludger","roleDisplay":"VerfasserIn","role":"aut","family":"Klimek","given":"Ludger"}],"title":[{"title_sort":"Cluster protocols in SCIT","subtitle":"enough evidence for practical use?","title":"Cluster protocols in SCIT"}],"relHost":[{"physDesc":[{"extent":"Online-Ressource"}],"origin":[{"publisherPlace":"London ; [Erscheinungsort nicht ermittelbar]","dateIssuedKey":"2001","publisher":"Lippincott Williams & Wilkins ; Ovid","dateIssuedDisp":"2001-"}],"id":{"issn":["1473-6322"],"eki":["325699453"],"zdb":["2039287-4"]},"pubHistory":["1.2001 -"],"part":{"year":"2010","pages":"1-6","issue":"3","volume":"10","text":"10(2010), 3 vom: Juni, Artikel-ID 188, Seite 1-6","extent":"6"},"note":["Gesehen am 17.10.05"],"type":{"media":"Online-Ressource","bibl":"periodical"},"disp":"Cluster protocols in SCIT enough evidence for practical use?Current opinion in allergy and clinical immunology","language":["eng"],"recId":"325699453","title":[{"title":"Current opinion in allergy and clinical immunology","title_sort":"Current opinion in allergy and clinical immunology"}]}],"physDesc":[{"extent":"6 S."}],"name":{"displayForm":["Oliver Pfaar, Sarah Leitzbach, Karl Hörmann and Ludger Klimek"]},"id":{"eki":["1843801094"],"doi":["10.1097/ACI.0b013e328339505c"]},"origin":[{"dateIssuedKey":"2010","dateIssuedDisp":"June 2010"}]} 
SRT |a PFAAROLIVECLUSTERPRO2010 

Ähnliche Einträge