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The FLUKA Monte Carlo code coupled with the local effect model for biological calculations in carbon ion therapy

Clinical Monte Carlo (MC) calculations for carbon ion therapy have to provide absorbed and RBE-weighted dose. The latter is defined as the product of the dose and the relative biological effectiveness (RBE). At the GSI Helmholtzzentrum für Schwerionenforschung as well as at the Heidelberg Ion Thera...

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Main Authors: Mairani, Andrea (Author) , Brons, Stephan (Author) , Cerutti, F. (Author) , Fassò, A. (Author) , Ferrari, A. (Author) , Krämer, M. (Author) , Parodi, Katia (Author) , Scholz, M. (Author) , Sommerer, Florian (Author)
Format: Article (Journal)
Language:English
Published: 20 July 2010
In: Physics in medicine and biology
Year: 2010, Volume: 55, Issue: 15, Pages: 4273-4289
ISSN:1361-6560
DOI:10.1088/0031-9155/55/15/006
Online Access:Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1088/0031-9155/55/15/006
Verlag, lizenzpflichtig, Volltext: https://iopscience.iop.org/article/10.1088/0031-9155/55/15/006
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Author Notes:A. Mairani, S. Brons, F. Cerutti, A. Fassò, A. Ferrari, M. Krämer, K. Parodi, M. Scholz and F. Sommerer
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Summary:Clinical Monte Carlo (MC) calculations for carbon ion therapy have to provide absorbed and RBE-weighted dose. The latter is defined as the product of the dose and the relative biological effectiveness (RBE). At the GSI Helmholtzzentrum für Schwerionenforschung as well as at the Heidelberg Ion Therapy Center (HIT), the RBE values are calculated according to the local effect model (LEM). In this paper, we describe the approach followed for coupling the FLUKA MC code with the LEM and its application to dose and RBE-weighted dose calculations for a superimposition of two opposed 12C ion fields as applied in therapeutic irradiations.
Item Description:Gesehen am 02.05.2023
Physical Description:Online Resource
ISSN:1361-6560
DOI:10.1088/0031-9155/55/15/006

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