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FGFR4 Arg388 genotype is associated with pathological complete response to neoadjuvant chemotherapy for primary breast cancer

A single-nucleotide polymorphism (SNP) in the FGFR4 gene is associated with poor prognosis in solid tumors. A recent study presented the first evidence that FGFR4 Arg388 could predict resistance to adjuvant chemotherapy in breast cancer. The present study evaluates the potential of this SNP to predi...

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Bibliographic Details
Main Authors: Marmé, Frederik (Author) , Werft, Wiebke (Author) , Benner, Axel (Author) , Burwinkel, Barbara (Author) , Sinn, Peter (Author) , Sohn, Christof (Author) , Lichter, Peter (Author) , Hahn, Meinhard (Author) , Schneeweiss, Andreas (Author)
Format: Article (Journal)
Language:English
Published: 10 February 2010
In: Annals of oncology
Year: 2010, Volume: 21, Issue: 8, Pages: 1636-1642
ISSN:1569-8041
DOI:10.1093/annonc/mdq017
Online Access:Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1093/annonc/mdq017
Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S0923753419394128
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Author Notes:F. Marmé, W. Werft, A. Benner, B. Burwinkel, P. Sinn, C. Sohn, P. Lichter, M. Hahn & A. Schneeweiss
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Summary:A single-nucleotide polymorphism (SNP) in the FGFR4 gene is associated with poor prognosis in solid tumors. A recent study presented the first evidence that FGFR4 Arg388 could predict resistance to adjuvant chemotherapy in breast cancer. The present study evaluates the potential of this SNP to predict response to neoadjuvant chemotherapy (NCT) for primary breast cancer (PBC).
Item Description:Gesehen am 04.05.2023
Physical Description:Online Resource
ISSN:1569-8041
DOI:10.1093/annonc/mdq017

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