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Overall morbidity after total minimally invasive keyhole oesophagectomy versus hybrid oesophagectomy (the MICkey trial): study protocol for a multicentre randomized controlled trial

Oesophageal cancer (EC) is the sixth leading cause of cancer death worldwide. Oesophageal resection is the only curative treatment option for EC which is frequently performed via an abdominal and right thoracic approach (Ivor-Lewis operation). This 2-cavity operation is associated with a high risk o...

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Main Authors: Klotz, Rosa (Author) , Diener, Markus K. (Author) , Schmidt, Thomas (Author) , Hackert, Thilo (Author) , Graf, Sandra (Author) , Fuchs, Hans F. (Author) , Grimminger, Peter (Author) , Egberts, Jan-Hendrick (Author) , Gockel, Ines (Author) , van der Sluis, Pieter C. (Author) , Dörr-Harim, Colette (Author) , Klose, Christina (Author) , Feißt, Manuel (Author) , Mihaljevic, André Leopold (Author)
Format: Article (Journal)
Language:English
Published: 10 March 2023
In: Trials
Year: 2023, Volume: 24, Pages: 1-16
ISSN:1468-6694
DOI:10.1186/s13063-023-07134-1
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s13063-023-07134-1
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Author Notes:Rosa Klotz, Markus K. Diener, Thomas Schmidt, Thilo Hackert, Sandra Graf, Hans F. Fuchs, Peter Grimminger, Jan-Hendrick Egberts, Ines Gockel, Pieter C. van der Sluis, Colette Doerr-Harim, Christina Klose, Manuel Feißt and Andre L. Mihaljevic
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Summary:Oesophageal cancer (EC) is the sixth leading cause of cancer death worldwide. Oesophageal resection is the only curative treatment option for EC which is frequently performed via an abdominal and right thoracic approach (Ivor-Lewis operation). This 2-cavity operation is associated with a high risk of major complications. To reduce postoperative morbidity, several minimally invasive techniques have been developed that can be broadly classified into either hybrid oesophagectomy (HYBRID-E) via laparoscopic/robotic abdominal and open thoracic surgery or total minimally invasive oesophagectomy (MIN-E). Both, HYBIRD-E and MIN-E, compare favourable to open oesophagectomy. However, there is still an evidence gap comparing HYBRID-E with MIN-E with regard to postoperative morbidity.
Item Description:Gesehen am 11.05.2023
Physical Description:Online Resource
ISSN:1468-6694
DOI:10.1186/s13063-023-07134-1

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