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Navigated liver biopsy using a novel soft tissue navigation system versus CT-guided liver biopsy in a porcine model: a prospective randomized trial

Rationale and Objectives - The aim of this prospective, randomized animal study was to compare a new computer guided needle-based navigation system for liver biopsy with conventional computed tomography (CT)-guided liver biopsy. Computer-navigated interventions provide continuous needle tracking dur...

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Hauptverfasser: Müller, Sascha A. (VerfasserIn) , Maier-Hein, Lena (VerfasserIn) , Tekbaş, Aysun (VerfasserIn) , Seitel, Alexander (VerfasserIn) , Ramsauer, Stefanie (VerfasserIn) , Radeleff, Boris (VerfasserIn) , Franz, Alfred Michael (VerfasserIn) , Tetzlaff, Ralf (VerfasserIn) , Mehrabi, Arianeb (VerfasserIn) , Wolf, Ivo (VerfasserIn) , Kauczor, Hans-Ulrich (VerfasserIn) , Meinzer, Hans-Peter (VerfasserIn) , Schmied, Bruno (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 8 September 2010
In: Academic radiology
Year: 2010, Jahrgang: 17, Heft: 10, Pages: 1282-1287
ISSN:1878-4046
DOI:10.1016/j.acra.2010.05.017
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.acra.2010.05.017
Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S1076633210002965
Volltext
Verfasserangaben:Sascha A. Müller MD, Lena Maier-Hein PhD, Aysun Tekbas, Alexander Seitel, Stefanie Ramsauer MD, Boris Radeleff MD, Alfred M. Franz, Ralf Tetzlaff MD, Arianeb Mehrabi MD, Ivo Wolf MD, Hans-Ulrich Kauczor MD, Hans-Peter Meinzer MD, Bruno M. Schmied MD
Beschreibung
Zusammenfassung:Rationale and Objectives - The aim of this prospective, randomized animal study was to compare a new computer guided needle-based navigation system for liver biopsy with conventional computed tomography (CT)-guided liver biopsy. Computer-navigated interventions provide continuous needle tracking during motion and deformation from patient respiration and movement. - Materials and Methods - Twenty artificial tumors of about 5 mm in diameter were injected into the livers of five pigs, each at a different site. Each tumor was targeted by conventional CT-guided and computer navigated intervention. Intervention was considered complete after successful tumor biopsy. Data on procedure time, number of CT scans performed, accuracy, and success rate were recorded. - Results - All tumors (100%) were biopsied successfully. Mean procedural time was comparable between the two techniques (20 ± 9 minutes conventional versus 20 ± 8 minutes navigation). Mean number of CT scans were 1.2 ± 0.4 with navigation and 6.1 ± 3.8 with the conventional technique (P < .01). The dose-length product in the conventional group was significantly higher (212 ± 116 mGy × cm) than in the navigated group (78 ± 22 mGy × cm; P < .001). Mean number of capsule penetrations was 4 ± 1 with navigation versus 2 ± 1 with the conventional technique (P < .001). - Conclusion - Computer-navigated liver biopsy may provide a promising and innovative device for easy, rapid, and successful liver biopsies with low morbidity. Further technical improvements and clinical studies in humans are required.
Beschreibung:Gesehen am 11.05.2023
Beschreibung:Online Resource
ISSN:1878-4046
DOI:10.1016/j.acra.2010.05.017

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