Heavy ion radiotherapy during pregnancy
Objective - To provide a safe particle therapy treatment for a pregnant woman with skull-base cancer. - Design - Case report. - Setting - University clinic. - Patient(s) - A 27-year-old woman diagnosed for a skull-base chordoma and whose pregnancy was found during the course of radiotherapy with acc...
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| Main Authors: | , , , , , , |
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| Format: | Article (Journal) Editorial |
| Language: | English |
| Published: |
20 May 2010
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| In: |
Fertility and sterility
Year: 2010, Volume: 94, Issue: 6, Pages: 2329.e5-2329.e7 |
| ISSN: | 1556-5653 |
| DOI: | 10.1016/j.fertnstert.2010.04.005 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.fertnstert.2010.04.005 Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S0015028210006023 
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| Author Notes: | Marc W. Münter, M.D., Marc Wengenroth, M.Sc., Georg Fehrenbacher, Ph.D., Dieter Schardt, Ph.D., Anna Nikoghosyan, M.D., Marco Durante, Ph.D., and Jürgen Debus, M.D., Ph.D. |
| Summary: | Objective - To provide a safe particle therapy treatment for a pregnant woman with skull-base cancer. - Design - Case report. - Setting - University clinic. - Patient(s) - A 27-year-old woman diagnosed for a skull-base chordoma and whose pregnancy was found during the course of radiotherapy with accelerated carbon ions. - Intervention(s) - Therapy was continued as scheduled, and fetal dose produced by photons and neutrons was measured at each radiotherapy fraction using passive and active monitors. - Main Outcome Measure(s) - Radiation dose to the uterus. Health of the mother and the newborn. - Result(s) - Total dose to the uterus was <0.2 mSv. About 30% of this dose was caused by neutrons. Magnetic resonance imaging of the skull base showed no evidence of recurrent disease in the mother. The child was healthy with normal development. - Conclusion(s) - Heavy ion cancer therapy produces a very low dose in distal organs. |
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| Item Description: | Gesehen am 11.05.2023 |
| Physical Description: | Online Resource |
| ISSN: | 1556-5653 |
| DOI: | 10.1016/j.fertnstert.2010.04.005 |