Heavy ion radiotherapy during pregnancy

Objective - To provide a safe particle therapy treatment for a pregnant woman with skull-base cancer. - Design - Case report. - Setting - University clinic. - Patient(s) - A 27-year-old woman diagnosed for a skull-base chordoma and whose pregnancy was found during the course of radiotherapy with acc...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Münter, Marc (VerfasserIn) , Wengenroth, Marc (VerfasserIn) , Fehrenbacher, Georg (VerfasserIn) , Schardt, Dieter (VerfasserIn) , Nikoghosyan, Anna (VerfasserIn) , Durante, Marco (VerfasserIn) , Debus, Jürgen (VerfasserIn)
Dokumenttyp: Article (Journal) Editorial
Sprache:Englisch
Veröffentlicht: 20 May 2010
In: Fertility and sterility
Year: 2010, Jahrgang: 94, Heft: 6, Pages: 2329.e5-2329.e7
ISSN:1556-5653
DOI:10.1016/j.fertnstert.2010.04.005
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.fertnstert.2010.04.005
Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S0015028210006023
Volltext
Verfasserangaben:Marc W. Münter, M.D., Marc Wengenroth, M.Sc., Georg Fehrenbacher, Ph.D., Dieter Schardt, Ph.D., Anna Nikoghosyan, M.D., Marco Durante, Ph.D., and Jürgen Debus, M.D., Ph.D.
Beschreibung
Zusammenfassung:Objective - To provide a safe particle therapy treatment for a pregnant woman with skull-base cancer. - Design - Case report. - Setting - University clinic. - Patient(s) - A 27-year-old woman diagnosed for a skull-base chordoma and whose pregnancy was found during the course of radiotherapy with accelerated carbon ions. - Intervention(s) - Therapy was continued as scheduled, and fetal dose produced by photons and neutrons was measured at each radiotherapy fraction using passive and active monitors. - Main Outcome Measure(s) - Radiation dose to the uterus. Health of the mother and the newborn. - Result(s) - Total dose to the uterus was <0.2 mSv. About 30% of this dose was caused by neutrons. Magnetic resonance imaging of the skull base showed no evidence of recurrent disease in the mother. The child was healthy with normal development. - Conclusion(s) - Heavy ion cancer therapy produces a very low dose in distal organs.
Beschreibung:Gesehen am 11.05.2023
Beschreibung:Online Resource
ISSN:1556-5653
DOI:10.1016/j.fertnstert.2010.04.005