Molecular characterisation of ERG, ETV1 and PTEN gene loci identifies patients at low and high risk of death from prostate cancer
The discovery of ERG/ETV 1 gene rearrangements and PTEN gene loss warrants investigation in a mechanism-based prognostic classification of prostate cancer (PCa). The study objective was to evaluate the potential clinical significance and natural history of different disease categories by combining E...
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| Hauptverfasser: | , , , , , , , , , , , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
26 January 2010
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| In: |
British journal of cancer
Year: 2010, Jahrgang: 102, Heft: 4, Pages: 678-684 |
| ISSN: | 1532-1827 |
| DOI: | 10.1038/sj.bjc.6605554 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1038/sj.bjc.6605554 Verlag, lizenzpflichtig, Volltext: https://www.nature.com/articles/6605554 |
| Verfasserangaben: | AHM Reid, G Attard, L Ambroisine, G Fisher, G Kovacs, D Brewer, J Clark, P Flohr, S Edwards, DM Berney, CS Foster, A Fletcher, WL Gerald, H Møller, VE Reuter, PT Scardino, J Cuzick, JS de Bono, and CS Cooper on behalf of the Transatlantic Prostate Group |
| Zusammenfassung: | The discovery of ERG/ETV 1 gene rearrangements and PTEN gene loss warrants investigation in a mechanism-based prognostic classification of prostate cancer (PCa). The study objective was to evaluate the potential clinical significance and natural history of different disease categories by combining ERG/ETV 1 gene rearrangements and PTEN gene loss status. |
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| Beschreibung: | Gesehen am 12.05.2023 |
| Beschreibung: | Online Resource |
| ISSN: | 1532-1827 |
| DOI: | 10.1038/sj.bjc.6605554 |