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Assessing general versus specific liability for externalizing problems in adolescence: concurrent and prospective prediction of symptoms of conduct disorder, ADHD, and substance use

This study explored the generality versus specificity of two trait-liability factors for externalizing problems—disinhibition and callousness—in the concurrent and prospective prediction of symptoms of conduct disorder, attention-deficit/hyperactivity disorder (ADHD), and substance use (i.e., alcoho...

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Main Authors: Perkins, Emily (Author) , Joyner, Keanan J. (Author) , Foell, Jens (Author) , Drislane, Laura E. (Author) , Brislin, Sarah J. (Author) , Frick, Paul J. (Author) , Yancey, James R. (Author) , Soto, Elia F. (Author) , Ganley, Colleen M. (Author) , Keel, Pamela K. (Author) , Sica, Claudio (Author) , Flor, Herta (Author) , Nees, Frauke (Author) , Banaschewski, Tobias (Author) , Bokde, Arun L. W. (Author) , Desrivières, Sylvane (Author) , Grigis, Antoine (Author) , Garavan, Hugh (Author) , Gowland, Penny (Author) , Heinz, Andreas (Author) , Ittermann, Bernd (Author) , Martinot, Jean-Luc (Author) , Paillère Martinot, Marie-Laure (Author) , Artiges, Eric (Author) , Papadopoulos Orfanos, Dimitri (Author) , Poustka, Luise (Author) , Hohmann, Sarah (Author) , Fröhner, Juliane H. (Author) , Smolka, Michael N. (Author) , Walter, Henrik (Author) , Whelan, Robert (Author) , Schumann, Gunter (Author) , Patrick, Christopher J. (Author)
Format: Article (Journal)
Language:English
Published: 2022
In: Journal of psychopathology and clinical science
Year: 2022, Volume: 131, Pages: 793-807
ISSN:2769-755X
DOI:10.1037/abn0000743
Online Access:Verlag, lizenzpflichtig, Volltext: https://dx.doi.org/10.1037/abn0000743
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Author Notes:Emily R. Perkins, Keanan J. Joyner, Jens Foell, Laura E. Drislane, Sarah J. Brislin, Paul J. Frick, James R. Yancey, Elia F. Soto, Colleen M. Ganley, Pamela K. Keel, Claudio Sica, Herta Flor, Frauke Nees, Tobias Banaschewski, Arun L. W. Bokde, Sylvane Desrivières, Antoine Grigis, Hugh Garavan, Penny Gowland, Andreas Heinz, Bernd Ittermann, Jean-Luc Martinot, Marie-Laure Paillère Martinot, Eric Artiges, Dimitri Papadopoulos Orfanos, Luise Poustka, Sarah Hohmann, Juliane H. Fröhner, Michael N. Smolka, Henrik Walter, Robert Whelan, Gunter Schumann, The IMAGEN Consortium, and Christopher J. Patrick
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Summary:This study explored the generality versus specificity of two trait-liability factors for externalizing problems—disinhibition and callousness—in the concurrent and prospective prediction of symptoms of conduct disorder, attention-deficit/hyperactivity disorder (ADHD), and substance use (i.e., alcohol use disorder and history of illicit substance use). Disinhibition involves an impulsive, unrestrained cognitive-behavioral style; callousness entails a dispositional lack of social-emotional sensitivity. Participants were European adolescents from the multisite IMAGEN project who completed questionnaires and clinical interviews at ages 14 (N = 1,504, Mage = 14.41, 51.13% female) and 16 (N = 1,407, Mage = 16.46, 51.88% female). Disinhibition was related concurrently and prospectively to greater symptoms of conduct disorder, ADHD, and alcohol use disorder; higher scores on a general externalizing factor; and greater likelihood of having tried an illicit substance. Callousness was selectively related to greater conduct disorder symptoms. These findings indicate disinhibition confers broad liability for externalizing spectrum disorders, perhaps due to its affiliated deficits in executive function. In contrast, callousness appears to represent more specific liability for antagonistic (aggressive/exploitative) forms of externalizing, as exemplified by antisocial behavior. Results support the utility of developmental-ontogenetic and hierarchical-dimensional models of psychopathology and have important implications for early assessment of risk for externalizing problems. (PsycInfo Database Record (c) 2022 APA, all rights reserved)
Item Description:Gesehen am 23.05.2023
Physical Description:Online Resource
ISSN:2769-755X
DOI:10.1037/abn0000743

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