Anticholinergic burden measures, symptoms, and fall-associated risk in older adults with polypharmacy: development and validation of a prognostic model

Anticholinergic burden has been associated with adverse outcomes such as falls. To date, no gold standard measure has been identified to assess anticholinergic burden, and no conclusion has been drawn on which of the different measure algorithms best predicts falls in older patients from general pra...

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Main Authors:	Dinh, Truc Sophia (Author) , Meid, Andreas (Author) , Rudolf, Henrik (Author) , Brückle, Maria-Sophie (Author) , González-González, Ana I. (Author) , Bencheva, Veronika (Author) , Gogolin, Matthias (Author) , Snell, Kym I. E. (Author) , Elders, Petra J. M. (Author) , Thürmann, Petra A. (Author) , Donner-Banzhoff, Norbert (Author) , Blom, Jeanet W. (Author) , Akker, Marjan van den (Author) , Gerlach, Ferdinand M. (Author) , Harder, Sebastian (Author) , Thiem, Ulrich (Author) , Glasziou, Paul (Author) , Haefeli, Walter E. (Author) , Muth, Christiane (Author)
Format:	Article (Journal)
Language:	English
Published:	January 23, 2023
In:	PLOS ONE Year: 2023, Volume: 18, Issue: 1, Pages: 1-19
ISSN:	1932-6203
DOI:	10.1371/journal.pone.0280907
Online Access:	Verlag, kostenfrei, Volltext: https://doi.org/10.1371/journal.pone.0280907 Verlag, kostenfrei, Volltext: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0280907
Author Notes:	Truc Sophia Dinh, Andreas D. Meid, Henrik Rudolf, Maria-Sophie Brueckle, Ana I. González-González, Veronika Bencheva, Matthias Gogolin, Kym I. E. Snell, Petra J. M. Elders, Petra A. Thuermann, Norbert Donner-Banzhoff, Jeanet W. Blom, Marjan van den Akker, Ferdinand M. Gerlach, Sebastian Harder, Ulrich Thiem, Paul P. Glasziou, Walter E. Haefeli, Christiane Muth