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Can we prevent fatal liver failure under valproate?

Valproic acid (VPA) has been used as an anticonvulsant for more than 30 years. Meanwhile, VPA has also been approved by the FDA for the treatment of bipolar disorders. We report the case of a 58-year-old female patient, who died from liver failure, probably due to treatment with VPA.

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Bibliographic Details
Main Authors: Schmid, Markus (Author) , Connemann, B. J. (Author) , Wolf, R. C. (Author) , Flechtenmacher, Christa (Author) , Eisenbach, Christoph (Author) , Schönfeldt-Lecuona, C. (Author)
Format: Article (Journal) Editorial
Language:English
Published: 25. Mai 2010
In: Pharmacopsychiatry
Year: 2010, Volume: 43, Issue: 5, Pages: 198-200
ISSN:1439-0795
DOI:10.1055/s-0030-1254125
Online Access:Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1055/s-0030-1254125
Verlag, lizenzpflichtig, Volltext: http://www.thieme-connect.de/DOI/DOI?10.1055/s-0030-1254125
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Author Notes:M.M. Schmid, B.J. Connemann, R.C. Wolf, C. Flechtenmacher, C. Eisenbach, C. Schönfeldt-Lecuona
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Summary:Valproic acid (VPA) has been used as an anticonvulsant for more than 30 years. Meanwhile, VPA has also been approved by the FDA for the treatment of bipolar disorders. We report the case of a 58-year-old female patient, who died from liver failure, probably due to treatment with VPA.
Item Description:Gesehen am 13.06.2023
Physical Description:Online Resource
ISSN:1439-0795
DOI:10.1055/s-0030-1254125

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