Analysis of the distribution shift of detected aneuploidies by age independent first trimester screening

First trimester screening (FTS) became standard in non-invasive testing for chromosomal abnormalities in early pregnancy. The individual risk is calculated on the basis of a general background risk, which refers to the maternal age. A new method, Advanced Firsttrimester Screening (AFS) excludes the...

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Bibliographic Details
Main Authors: Schmidt, Peter (Author) , Hörmansdörfer, Cindy (Author) , Golatta, Michael (Author) , Scharf, Alexander (Author)
Format: Article (Journal)
Language:English
Published: 2010
In: Archives of gynecology and obstetrics
Year: 2010, Volume: 281, Issue: 3, Pages: 393-399
ISSN:1432-0711
DOI:10.1007/s00404-009-1137-6
Online Access:Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1007/s00404-009-1137-6
Verlag, lizenzpflichtig, Volltext: https://link.springer.com/article/10.1007/s00404-009-1137-6
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Author Notes:Peter Schmidt, C. Hörmansdörfer, M. Golatta, A. Scharf
Description
Summary:First trimester screening (FTS) became standard in non-invasive testing for chromosomal abnormalities in early pregnancy. The individual risk is calculated on the basis of a general background risk, which refers to the maternal age. A new method, Advanced Firsttrimester Screening (AFS) excludes the background risk in its algorithm. This study had the aim to analyze how the detection of aneuploidies is influenced by the in- or exclusion of the maternal age in the risk calculation.
Item Description:Gesehen am 13.06.2023
Physical Description:Online Resource
ISSN:1432-0711
DOI:10.1007/s00404-009-1137-6