Slice2Volume: fusion of multimodal medical imaging and light microscopy data of irradiation-injured brain tissue in 3D

Comprehending cellular changes of radiation-induced brain injury is crucial to prevent and treat the pathology. We provide a unique open dataset of proton-irradiated mouse brains consisting of medical imaging, radiation dose simulations, and large-scale microscopy images, all registered into a commo...

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Main Authors: Soltwedel, Johannes (Author) , Suckert, Theresa (Author) , Beyreuther, Elke (Author) , Schneider, Moritz (Author) , Boucsein, Marc (Author) , Bodenstein, Elisabeth (Author) , Nexhipi, Sindi (Author) , Stolz-Kieslich, Liane (Author) , Krause, Mechthild (Author) , von Neubeck, Cläre (Author) , Haase, Robert (Author) , Lühr, Armin (Author) , Dietrich, Antje (Author)
Format: Article (Journal)
Language:English
Published: 20 March 2023
In: Radiotherapy and oncology
Year: 2023, Volume: 182, Pages: 1-7
ISSN:1879-0887
DOI:10.1016/j.radonc.2023.109591
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.radonc.2023.109591
Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S0167814023001299
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Author Notes:Johannes Soltwedel, Theresa Suckert, Elke Beyreuther, Moritz Schneider, Marc Boucsein, Elisabeth Bodenstein, Sindi Nexhipi, Liane Stolz-Kieslich, Mechthild Krause, Cläre von Neubeck, Robert Haase, Armin Lühr, Antje Dietrich
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Summary:Comprehending cellular changes of radiation-induced brain injury is crucial to prevent and treat the pathology. We provide a unique open dataset of proton-irradiated mouse brains consisting of medical imaging, radiation dose simulations, and large-scale microscopy images, all registered into a common coordinate system. This allows dose-dependent analyses on single-cell level.
Item Description:Online verfügbar 28. Februar 2023, Artikelversion 20. März 2023
Gesehen am 15.06.2023
Physical Description:Online Resource
ISSN:1879-0887
DOI:10.1016/j.radonc.2023.109591