Regulation patterns in signaling networks of cancer
Formation of cellular malignancy results from the disruption of fine tuned signaling homeostasis for proliferation, accompanied by mal-functional signals for differentiation, cell cycle and apoptosis. We wanted to observe central signaling characteristics on a global view of malignant cells which ha...
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| Main Authors: | , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
26 November 2010
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| In: |
BMC systems biology
Year: 2010, Volume: 4, Issue: 1, Pages: 1-12 |
| ISSN: | 1752-0509 |
| DOI: | 10.1186/1752-0509-4-162 |
| Online Access: | Resolving-System, kostenfrei, Volltext: https://doi.org/10.1186/1752-0509-4-162 Verlag, kostenfrei, Volltext: https://bmcsystbiol.biomedcentral.com/articles/10.1186/1752-0509-4-162 
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| Author Notes: | Gunnar Schramm, Nandakumar Kannabiran, Rainer König |
| Summary: | Formation of cellular malignancy results from the disruption of fine tuned signaling homeostasis for proliferation, accompanied by mal-functional signals for differentiation, cell cycle and apoptosis. We wanted to observe central signaling characteristics on a global view of malignant cells which have evolved to selfishness and independence in comparison to their non-malignant counterparts that fulfill well defined tasks in their sample. |
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| Item Description: | Gesehen am 29.06.2023 |
| Physical Description: | Online Resource |
| ISSN: | 1752-0509 |
| DOI: | 10.1186/1752-0509-4-162 |