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Sex differences and adherence of patients treated with wearable cardioverter-defibrillator: insights from an international multicenter register

Aims: Treatment with the wearable cardioverter defibrillator (WCD) may protect against sudden cardiac death (SCD) as a bridging therapy until a cardioverter-defibrillator may be implanted. We analyzed in a multicenter setting a consecutive patient cohort wearing WCD to explore sex differences. Metho...

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Main Authors: Abumayyaleh, Mohammad S. A. (Author) , Dreher, Tobias C. (Author) , Rosenkaimer, Stephanie L. (Author) , Röger, Susanne (Author) , Erath, Julia W. (Author) , Klein, Norbert (Author) , Kovacs, Boldizsar (Author) , Duru, Firat (Author) , Saguner, Ardan M. (Author) , El-Battrawy, Ibrahim (Author) , Akın, Ibrahim (Author)
Format: Article (Journal)
Language:English
Published: 05 August 2022
In: Journal of cardiovascular electrophysiology
Year: 2022, Volume: 33, Issue: 11, Pages: 2243-2249
ISSN:1540-8167
DOI:10.1111/jce.15648
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1111/jce.15648
Verlag, kostenfrei, Volltext: http://onlinelibrary.wiley.com/doi/abs/10.1111/jce.15648
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Author Notes:Mohammad Abumayyaleh, Tobias C. Dreher, Stephanie Rosenkaimer, Susanne Röger, Julia W. Erath, Norbert Klein, Boldizsar Kovacs, Firat Duru, Ardan M. Saguner, Ibrahim El-Battrawy, Ibrahim Akin
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Summary:Aims: Treatment with the wearable cardioverter defibrillator (WCD) may protect against sudden cardiac death (SCD) as a bridging therapy until a cardioverter-defibrillator may be implanted. We analyzed in a multicenter setting a consecutive patient cohort wearing WCD to explore sex differences. Methods and Results: We analyzed 708 consecutive patients, 579 (81.8%) from whom were males and 129 (18.2%) females (age, 60.5 ± 14 vs. 61.6 ± 17 years old; p = .44). While the rate of ischemic cardiomyopathy (ICM) as a cause of prescription of WCD was significantly higher in males as compared to females (42.7% vs. 26.4%; p = .001), females received it more frequently due to nonischemic cardiomyopathy (NICM) (55.8% vs. 42.7%); p = .009). The wear time of WCD was equivalent in both groups (21.1 ± 4.3 h/days in males vs. 21.5 ± 4.4 h/days in females; p = .27; and 62.6 ± 44.3 days in males vs. 56.5 ± 39 days in females; p = .15). Mortality was comparable in both groups at 2-year-follow-up (6.8% in males vs. 9.7% in females; p = .55). Appropriate WCD shocks and the incidence of ICD implantations were similar in both groups (2.4% in males vs. 3.9% in females; p = .07) (35.1% in males vs. 31.8% in females; p = .37), respectively. In age tertile analysis, compliance was observed more in 73-91 years old group as compared with 14-51 years old group (87.8% vs. 68.3%; p < .001). Conclusion: Compliance for wearing WCD was excellent regardless of sex. Furthermore, mortality and the incidence of ICD implantations were comparable in both sexes. Appropriate WCD shocks were similar in both sexes.
Item Description:Gesehen am 03.07.2023
Physical Description:Online Resource
ISSN:1540-8167
DOI:10.1111/jce.15648

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