Sex differences and adherence of patients treated with wearable cardioverter-defibrillator: insights from an international multicenter register

Aims: Treatment with the wearable cardioverter defibrillator (WCD) may protect against sudden cardiac death (SCD) as a bridging therapy until a cardioverter-defibrillator may be implanted. We analyzed in a multicenter setting a consecutive patient cohort wearing WCD to explore sex differences. Metho...

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Hauptverfasser: Abumayyaleh, Mohammad S. A. (VerfasserIn) , Dreher, Tobias C. (VerfasserIn) , Rosenkaimer, Stephanie L. (VerfasserIn) , Röger, Susanne (VerfasserIn) , Erath, Julia W. (VerfasserIn) , Klein, Norbert (VerfasserIn) , Kovacs, Boldizsar (VerfasserIn) , Duru, Firat (VerfasserIn) , Saguner, Ardan M. (VerfasserIn) , El-Battrawy, Ibrahim (VerfasserIn) , Akın, Ibrahim (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 05 August 2022
In: Journal of cardiovascular electrophysiology
Year: 2022, Jahrgang: 33, Heft: 11, Pages: 2243-2249
ISSN:1540-8167
DOI:10.1111/jce.15648
Online-Zugang:Verlag, kostenfrei, Volltext: https://doi.org/10.1111/jce.15648
Verlag, kostenfrei, Volltext: http://onlinelibrary.wiley.com/doi/abs/10.1111/jce.15648
Volltext
Verfasserangaben:Mohammad Abumayyaleh, Tobias C. Dreher, Stephanie Rosenkaimer, Susanne Röger, Julia W. Erath, Norbert Klein, Boldizsar Kovacs, Firat Duru, Ardan M. Saguner, Ibrahim El-Battrawy, Ibrahim Akin

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520 |a Aims: Treatment with the wearable cardioverter defibrillator (WCD) may protect against sudden cardiac death (SCD) as a bridging therapy until a cardioverter-defibrillator may be implanted. We analyzed in a multicenter setting a consecutive patient cohort wearing WCD to explore sex differences. Methods and Results: We analyzed 708 consecutive patients, 579 (81.8%) from whom were males and 129 (18.2%) females (age, 60.5 ± 14 vs. 61.6 ± 17 years old; p = .44). While the rate of ischemic cardiomyopathy (ICM) as a cause of prescription of WCD was significantly higher in males as compared to females (42.7% vs. 26.4%; p = .001), females received it more frequently due to nonischemic cardiomyopathy (NICM) (55.8% vs. 42.7%); p = .009). The wear time of WCD was equivalent in both groups (21.1 ± 4.3 h/days in males vs. 21.5 ± 4.4 h/days in females; p = .27; and 62.6 ± 44.3 days in males vs. 56.5 ± 39 days in females; p = .15). Mortality was comparable in both groups at 2-year-follow-up (6.8% in males vs. 9.7% in females; p = .55). Appropriate WCD shocks and the incidence of ICD implantations were similar in both groups (2.4% in males vs. 3.9% in females; p = .07) (35.1% in males vs. 31.8% in females; p = .37), respectively. In age tertile analysis, compliance was observed more in 73-91 years old group as compared with 14-51 years old group (87.8% vs. 68.3%; p < .001). Conclusion: Compliance for wearing WCD was excellent regardless of sex. Furthermore, mortality and the incidence of ICD implantations were comparable in both sexes. Appropriate WCD shocks were similar in both sexes. 
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