Validation of a German translation of the CARE questionnaire and its implementation as electronic PROM to assess patient-reported postoperative convalescence and recovery after major urological surgery

Purpose  To validate a German translation of the convalescence and recovery evaluation (CARE) as an electronic patientreported outcome measure (ePROM) and use it to assess recovery after major urological surgery. - Methods  The CARE questionnaire was provided to patients scheduled for major urologic...

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Main Authors: Wessels, Frederik (Author) , Lenhart, Maximilian (Author) , Neuberger, Manuel (Author) , Mühlbauer, Julia (Author) , Huber, Johannes (Author) , Breyer, Johannes (Author) , Nuhn, Philipp (Author) , Michel, Maurice Stephan (Author) , Koenig, Julian (Author) , Kriegmair, Maximilian (Author)
Format: Article (Journal)
Language:English
Published: 8 May 2021
In: World journal of urology
Year: 2021, Volume: 39, Issue: 10, Pages: 3979-3991
ISSN:1433-8726
DOI:10.1007/s00345-021-03713-6
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1007/s00345-021-03713-6
Verlag, kostenfrei, Volltext: https://link.springer.com/10.1007/s00345-021-03713-6
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Author Notes:Frederik Wessels, Maximilian Lenhart, Manuel Neuberger, Julia Mühlbauer, Johannes Huber, Johannes Breyer, Philipp Nuhn, Maurice S.Michel, Julian Koenig & Maximilian C.Kriegmair
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Summary:Purpose  To validate a German translation of the convalescence and recovery evaluation (CARE) as an electronic patientreported outcome measure (ePROM) and use it to assess recovery after major urological surgery. - Methods  The CARE questionnaire was provided to patients scheduled for major urological surgery preoperatively, at discharge and 6 weeks postoperatively, using an ePROM system. Cronbach’s alpha, inter-scale correlations and confirmatory factor analysis (CFA) were used to validate the translation. Mixed linear regression models were used to identify factors influencing CARE results, and a multivariable logistic regression analysis was done to determine the predictive value of CARE results on quality of life (QoL). - Results  A total of 283 patients undergoing prostatectomy (n = 146, 51%), partial/radical nephrectomy (n = 70, 25%) or cystectomy (n = 67, 24%) responded to the survey. Internal consistency was high (α = 0.649-0.920) and the CFA showed a factor loading > 0.5 in 17/27 items. Significant main effects were found for the time of survey and type of surgery, while a time by type interaction was only found for the gastrointestinal subscale ( (24) = 30.37, p < 0.0001) and the total CARE score (TCS) ( (24) = 13.47, p = 0.009) for cystectomy patients, meaning a greater score decrease at discharge and lower level of recovery at follow-up. Complications demonstrated a significant negative effect on the TCS ( (22) = 8.61, p = 0.014). A high TCS at discharge was an independent predictor of a high QLQ-C30 QoL score at follow-up (OR = 5.26, 95%-CI 1.42-19.37, p = 0.013). - Conclusion  This German translation of the CARE can serve as a valid ePROM to measure recovery and predict QoL after major urological surgery.
Item Description:Gesehen am 03.07.2023
Physical Description:Online Resource
ISSN:1433-8726
DOI:10.1007/s00345-021-03713-6