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HIPEC-induced acute kidney injury: a retrospective clinical study and preclinical model

Hyperthermic intraperitoneal chemotherapy (HIPEC) combined with cytoreductive surgery (CRS) is the treatment of choice for selected patients with peritoneal malignancies. HIPEC is accompanied by moderate-to-high patient morbidity, including acute kidney injury. The significance of nephrotoxic agents...

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Bibliographic Details
Main Authors: Liesenfeld, Lukas (Author) , Wagner, Benedikt (Author) , Hillebrecht, Christian (Author) , Brune, Maik (Author) , Eckert, Christoph (Author) , Klose, Johannes (Author) , Schmidt, Thomas (Author) , Büchler, Markus W. (Author) , Schneider, Martin (Author)
Format: Article (Journal)
Language:English
Published: 2022
In: Annals of surgical oncology
Year: 2022, Volume: 29, Issue: 1, Pages: 139-151
ISSN:1534-4681
DOI:10.1245/s10434-021-10376-5
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1245/s10434-021-10376-5
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Author Notes:Lukas F. Liesenfeld, Benedikt Wagner, H. Christian Hillebrecht, Maik Brune, Christoph Eckert, Johannes Klose, Thomas Schmidt, Markus W. Büchler, Martin Schneider
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Summary:Hyperthermic intraperitoneal chemotherapy (HIPEC) combined with cytoreductive surgery (CRS) is the treatment of choice for selected patients with peritoneal malignancies. HIPEC is accompanied by moderate-to-high patient morbidity, including acute kidney injury. The significance of nephrotoxic agents such as cisplatin versus hyperthermia in HIPEC-induced nephrotoxicity has not been defined yet.
Item Description:Online veröffentlicht: 14. Juli 2021
Gesehen am 17.07.2023
Physical Description:Online Resource
ISSN:1534-4681
DOI:10.1245/s10434-021-10376-5

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