Semiallogenic fusions of MSI+tumor cells and activated B cells induce MSI-specific T cell responses
Various strategies have been developed to transfer tumor-specific antigens into antigen presenting cells in order to induce cytotoxic T cell responses against tumor cells. One approach uses cellular vaccines based on fusions of autologous antigen presenting cells and allogeneic tumor cells. The fusi...
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| Main Authors: | , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
26 September 2011
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| In: |
BMC cancer
Year: 2011, Volume: 11, Pages: 1-10 |
| ISSN: | 1471-2407 |
| DOI: | 10.1186/1471-2407-11-410 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/1471-2407-11-410
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| Author Notes: | Yvette Garbe, Ulrike Klier and Michael Linnebacher |
| Summary: | Various strategies have been developed to transfer tumor-specific antigens into antigen presenting cells in order to induce cytotoxic T cell responses against tumor cells. One approach uses cellular vaccines based on fusions of autologous antigen presenting cells and allogeneic tumor cells. The fusion cells combine antigenicity of the tumor cell with optimal immunostimulatory capacity of the antigen presenting cells. |
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| Item Description: | Gesehen am 17.07.2023 Im Titel ist das Pluszeichen "+" hochgestellt |
| Physical Description: | Online Resource |
| ISSN: | 1471-2407 |
| DOI: | 10.1186/1471-2407-11-410 |