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Comparison of different dose accumulation strategies to estimate organ doses after stereotactic magnetic resonance-guided adaptive radiotherapy

Re-irradiation is frequently performed in the era of precision oncology, but previous doses to organs-at-risk (OAR) must be assessed to avoid cumulative overdoses. Stereotactic magnetic resonance-guided online adaptive radiotherapy (SMART) enables highly precise ablation of tumors close to OAR. Howe...

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Main Authors: Regnery, Sebastian (Author) , Leiner, Lukas (Author) , Buchele, Carolin (Author) , Hoegen-Saßmannshausen, Philipp (Author) , Sandrini, Elisabetta (Author) , Held, Thomas (Author) , Deng, Maximilian (Author) , Eichkorn, Tanja (Author) , Rippke, Carolin (Author) , Renkamp, Claudia Katharina (Author) , König, Laila (Author) , Uzun-Lang, Kristin (Author) , Adeberg, Sebastian (Author) , Debus, Jürgen (Author) , Klüter, Sebastian (Author) , Hörner-Rieber, Juliane (Author)
Format: Article (Journal)
Language:English
Published: 29 May 2023
In: Radiation oncology
Year: 2023, Volume: 18, Pages: 1-12
ISSN:1748-717X
DOI:10.1186/s13014-023-02284-7
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s13014-023-02284-7
Verlag, kostenfrei, Volltext: https://ro-journal.biomedcentral.com/articles/10.1186/s13014-023-02284-7
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Author Notes:Sebastian Regnery, Lukas Leiner, Carolin Buchele, Philipp Hoegen, Elisabetta Sandrini, Thomas Held, Maximilian Deng, Tanja Eichkorn, Carolin Rippke, C. Katharina Renkamp, Laila König, Kristin Lang, Sebastian Adeberg, Jürgen Debus, Sebastian Klüter and Juliane Hörner-Rieber
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Summary:Re-irradiation is frequently performed in the era of precision oncology, but previous doses to organs-at-risk (OAR) must be assessed to avoid cumulative overdoses. Stereotactic magnetic resonance-guided online adaptive radiotherapy (SMART) enables highly precise ablation of tumors close to OAR. However, OAR doses may change considerably during adaptive treatment, which complicates potential re-irradiation. We aimed to compare the baseline plan with different dose accumulation techniques to inform re-irradiation.
Item Description:Gesehen am 30.11.2023
Physical Description:Online Resource
ISSN:1748-717X
DOI:10.1186/s13014-023-02284-7

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