Cover Image

Chromosomal radiosensitivity in oncological and non-oncological patients with rheumatoid arthritis and connective tissue diseases

The risk of developing late radiotoxicity after radiotherapy in patients with high chromosomal radiosensitivity after radiotherapy could potentially be higher compared to the risk in patients with average radiosensitivity. In case of extremely high radiosensitivity, dose reduction may be appropriate...

Full description

Saved in:
Bibliographic Details
Main Authors: Rzepka, Dinah (Author) , Schenker, Hannah (Author) , Geinitz, Hans (Author) , Silberberger, Elisabeth (Author) , Kaudewitz, Dorothee (Author) , Schuster, Barbara (Author) , Kuhlmann, Lukas (Author) , Schonath, Miriam (Author) , Ayala Gaona, Horacio (Author) , Aschacher, Bernhard (Author) , Fietkau, Rainer (Author) , Schett, Georg (Author) , Distel, Luitpold (Author)
Format: Article (Journal)
Language:English
Published: 07 June 2023
In: Radiation oncology
Year: 2023, Volume: 18, Pages: 1-13
ISSN:1748-717X
DOI:10.1186/s13014-023-02291-8
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s13014-023-02291-8
Verlag, kostenfrei, Volltext: https://ro-journal.biomedcentral.com/articles/10.1186/s13014-023-02291-8
Get full text
Author Notes:Dinah Rzepka, Hannah Schenker, Hans Geinitz, Elisabeth Silberberger, Dorothee Kaudewitz, Barbara Schuster, Lukas Kuhlmann, Miriam Schonath, Horacio Ayala Gaona, Bernhard Aschacher, Rainer Fietkau, Georg Schett and Luitpold Distel
Description
Summary:The risk of developing late radiotoxicity after radiotherapy in patients with high chromosomal radiosensitivity after radiotherapy could potentially be higher compared to the risk in patients with average radiosensitivity. In case of extremely high radiosensitivity, dose reduction may be appropriate. Some rheumatic diseases (RhD), including connective tissue diseases (CTDs) appear to be associated with higher radiosensitivity. The question arises as to whether patients with rheumatoid arthritis (RA) also generally have a higher radiosensitivity and whether certain parameters could indicate clues to high radiosensitivity in RA patients which would then need to be further assessed before radiotherapy.
Item Description:Gesehen am 21.11.2023
Physical Description:Online Resource
ISSN:1748-717X
DOI:10.1186/s13014-023-02291-8

Similar Items