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SMARCA4-deficient undifferentiated tumor achieved by transbronchial mediastinal cryobiopsy additional to needle aspiration

Lung cancer is the leading cause of deaths from malignant neoplasms worldwide, and a satisfactory biopsy that allows for histological and other analyses is critical for its diagnosis. Guidelines have recommended endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) as the refe...

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Main Authors: Zhang, Jing (Author) , Zhou, Dong (Author) , Fu, Wan-Lei (Author) , Guo, Jie-Ru (Author) , Cheng, Tian-Le (Author) , Jiang, Yun-Qiu (Author) , Huang, Zan-Sheng (Author) , Herth, Felix (Author) , Fan, Ye (Author)
Format: Article (Journal)
Language:English
Published: June 2023
In: Respiration
Year: 2023, Volume: 102, Issue: 6, Pages: 458-462
ISSN:1423-0356
DOI:10.1159/000529986
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1159/000529986
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Author Notes:Jing Zhang, Dong Zhou, Wan-Lei Fu, Jie-Ru Guo, Tian-Le Cheng, Yun-Qiu Jiang, Zan-Sheng Huang, Felix J. Herth, Ye Fan
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Summary:Lung cancer is the leading cause of deaths from malignant neoplasms worldwide, and a satisfactory biopsy that allows for histological and other analyses is critical for its diagnosis. Guidelines have recommended endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) as the reference standard for the staging of lung cancer. However, the relatively limited sample volume retrieved by needle aspiration might restrict the diagnostic capacity of EBUS-TBNA in other uncommon thoracic tumors. Transbronchial mediastinal cryobiopsy is a recently developed sampling strategy for mediastinal lesions, which demonstrates added diagnostic value to conventional needle aspiration. Here, we present a case of thoracic SMARCA4-deficient undifferentiated tumor successfully diagnosed by mediastinal cryobiopsy additional to EBUS-TBNA.
Item Description:Online veröffentlicht: 24. Mai 2023
Gesehen am 31.07.2023
Physical Description:Online Resource
ISSN:1423-0356
DOI:10.1159/000529986

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