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α-catenin interaction with YAP/FoxM1/TEAD-induced CEP55 supports liver cancer cell migration

Adherens junctions (AJs) facilitate cell-cell contact and contribute to cellular communication as well as signaling under physiological and pathological conditions. Aberrant expression of AJ proteins is frequently observed in human cancers; however, how these factors contribute to tumorigenesis is p...

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Main Authors: Tang, Yingyue (Author) , Thiess, Lena (Author) , Weiler, Sofia Maria Elisabeth (Author) , Tóth, Marcell (Author) , Rose, Fabian (Author) , Merker, Sabine (Author) , Ruppert, Thomas (Author) , Schirmacher, Peter (Author) , Breuhahn, Kai (Author)
Format: Article (Journal)
Language:English
Published: 2023
In: Cell communication and signaling
Year: 2023, Volume: 21, Pages: 1-19
ISSN:1478-811X
DOI:10.1186/s12964-023-01169-2
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s12964-023-01169-2
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Author Notes:Yingyue Tang, Lena Thiess, Sofia M.E. Weiler, Marcell Tóth, Fabian Rose, Sabine Merker, Thomas Ruppert, Peter Schirmacher and Kai Breuhahn
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Summary:Adherens junctions (AJs) facilitate cell-cell contact and contribute to cellular communication as well as signaling under physiological and pathological conditions. Aberrant expression of AJ proteins is frequently observed in human cancers; however, how these factors contribute to tumorigenesis is poorly understood. In addition, for some factors such as α‐catenin contradicting data has been described. In this study we aim to decipher how the AJ constituent α‐catenin contributes to liver cancer formation.
Item Description:Veröffentlicht: 28. Juni 2023
Gesehen am 17.08.2023
Physical Description:Online Resource
ISSN:1478-811X
DOI:10.1186/s12964-023-01169-2

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