Buchumschlag

α-catenin interaction with YAP/FoxM1/TEAD-induced CEP55 supports liver cancer cell migration

Adherens junctions (AJs) facilitate cell-cell contact and contribute to cellular communication as well as signaling under physiological and pathological conditions. Aberrant expression of AJ proteins is frequently observed in human cancers; however, how these factors contribute to tumorigenesis is p...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Tang, Yingyue (VerfasserIn) , Thiess, Lena (VerfasserIn) , Weiler, Sofia Maria Elisabeth (VerfasserIn) , Tóth, Marcell (VerfasserIn) , Rose, Fabian (VerfasserIn) , Merker, Sabine (VerfasserIn) , Ruppert, Thomas (VerfasserIn) , Schirmacher, Peter (VerfasserIn) , Breuhahn, Kai (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 2023
In: Cell communication and signaling
Year: 2023, Jahrgang: 21, Pages: 1-19
ISSN:1478-811X
DOI:10.1186/s12964-023-01169-2
Online-Zugang:Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s12964-023-01169-2
Volltext
Verfasserangaben:Yingyue Tang, Lena Thiess, Sofia M.E. Weiler, Marcell Tóth, Fabian Rose, Sabine Merker, Thomas Ruppert, Peter Schirmacher and Kai Breuhahn
Beschreibung
Zusammenfassung:Adherens junctions (AJs) facilitate cell-cell contact and contribute to cellular communication as well as signaling under physiological and pathological conditions. Aberrant expression of AJ proteins is frequently observed in human cancers; however, how these factors contribute to tumorigenesis is poorly understood. In addition, for some factors such as α‐catenin contradicting data has been described. In this study we aim to decipher how the AJ constituent α‐catenin contributes to liver cancer formation.
Beschreibung:Veröffentlicht: 28. Juni 2023
Gesehen am 17.08.2023
Beschreibung:Online Resource
ISSN:1478-811X
DOI:10.1186/s12964-023-01169-2

Ähnliche Einträge