α-catenin interaction with YAP/FoxM1/TEAD-induced CEP55 supports liver cancer cell migration
Adherens junctions (AJs) facilitate cell-cell contact and contribute to cellular communication as well as signaling under physiological and pathological conditions. Aberrant expression of AJ proteins is frequently observed in human cancers; however, how these factors contribute to tumorigenesis is p...
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| Hauptverfasser: | , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
2023
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| In: |
Cell communication and signaling
Year: 2023, Jahrgang: 21, Pages: 1-19 |
| ISSN: | 1478-811X |
| DOI: | 10.1186/s12964-023-01169-2 |
| Online-Zugang: | Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s12964-023-01169-2
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| Verfasserangaben: | Yingyue Tang, Lena Thiess, Sofia M.E. Weiler, Marcell Tóth, Fabian Rose, Sabine Merker, Thomas Ruppert, Peter Schirmacher and Kai Breuhahn |
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| 245 | 1 | 0 | |a α-catenin interaction with YAP/FoxM1/TEAD-induced CEP55 supports liver cancer cell migration |c Yingyue Tang, Lena Thiess, Sofia M.E. Weiler, Marcell Tóth, Fabian Rose, Sabine Merker, Thomas Ruppert, Peter Schirmacher and Kai Breuhahn |
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| 520 | |a Adherens junctions (AJs) facilitate cell-cell contact and contribute to cellular communication as well as signaling under physiological and pathological conditions. Aberrant expression of AJ proteins is frequently observed in human cancers; however, how these factors contribute to tumorigenesis is poorly understood. In addition, for some factors such as α‐catenin contradicting data has been described. In this study we aim to decipher how the AJ constituent α‐catenin contributes to liver cancer formation. | ||
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| 650 | 4 | |a Hippo pathway | |
| 650 | 4 | |a TEA domain transcription factors | |
| 650 | 4 | |a Yes-associated protein | |
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