Cover Image

EGF receptor modulates HEV entry in human hepatocytes

Being the most common cause of acute viral hepatitis with >20 million cases per year and 70,000 deaths annually, HEV presents a long-neglected and underinvestigated health burden. Although the entry process of viral particles is an attractive target for pharmacological intervention, druggable hos...

Full description

Saved in:
Bibliographic Details
Main Authors: Haase, Jil Alexandra (Author) , Burkard, Thomas L. (Author) , Brüggemann, Yannick (Author) , Gömer, André (Author) , Meister, Toni L. (Author) , Fu, Rebecca Menhua (Author) , Mehnert, Ann-Kathrin (Author) , Dao Thi, Viet Loan (Author) , Behrendt, Patrick (Author) , Durantel, David (Author) , Broering, Ruth (Author) , Vondran, Florian W. R. (Author) , Todt, Daniel (Author) , Kinast, Volker (Author) , Steinmann, Eike (Author)
Format: Article (Journal)
Language:English
Published: February 7, 2023
In: Hepatology
Year: 2023, Volume: 77, Issue: 6, Pages: 2104-2117
ISSN:1527-3350
DOI:10.1097/HEP.0000000000000308
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1097/HEP.0000000000000308
Verlag, lizenzpflichtig, Volltext: https://journals.lww.com/hep/fulltext/2023/06000/egf_receptor_modulates_hev_entry_in_human.24.aspx
Get full text
Author Notes:Jil A. Schrader, Thomas L. Burkard, Yannick Brüggemann, André Gömer, Toni L. Meister, Rebecca M. Fu, Ann-Kathrin Mehnert, Viet L. Dao Thi, Patrick Behrendt, David Durantel, Ruth Broering, Florian W.R. Vondran, Daniel Todt, Volker Kinast, Eike Steinmann
Description
Summary:Being the most common cause of acute viral hepatitis with >20 million cases per year and 70,000 deaths annually, HEV presents a long-neglected and underinvestigated health burden. Although the entry process of viral particles is an attractive target for pharmacological intervention, druggable host factors to restrict HEV entry have not been identified so far. ...
Item Description:Gesehen am 22.11.2023
Physical Description:Online Resource
ISSN:1527-3350
DOI:10.1097/HEP.0000000000000308

Similar Items