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Long-term safety of methylphenidate in children and adolescents with ADHD: 2-year outcomes of the Attention Deficit Hyperactivity Disorder Drugs Use Chronic Effects (ADDUCE) study

Methylphenidate is the most frequently prescribed medication for the treatment of ADHD in children and adolescents in many countries. Although many randomised controlled trials support short-term efficacy, tolerability, and safety, data on long-term safety and tolerability are scarce. The aim of th...

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Main Authors: Man, Kenneth K. C. (Author) , Häge, Alexander (Author) , Banaschewski, Tobias (Author) , Dittmann, Ralf (Author)
Format: Article (Journal)
Language:English
Published: May 2023
In: The lancet. Psychiatry
Year: 2023, Volume: 10, Issue: 5, Pages: 323-333
ISSN:2215-0374
DOI:10.1016/S2215-0366(23)00042-1
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/S2215-0366(23)00042-1
Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S2215036623000421
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Author Notes:Kenneth K.C. Man, Alexander Häge, Tobias Banaschewski, Sarah K. Inglis, Jan Buitelaar, Sara Carucci, Marina Danckaerts, Ralf W. Dittmann, Bruno Falissard, Peter Garas, Chris Hollis, Kerstin Konrad, Hanna Kovshoff, Elizabeth Liddle, Suzanne McCarthy, Antje Neubert, Peter Nagy, Eric Rosenthal, Edmund J.S. Sonuga-Barke, Alessandro Zuddas, Ian C.K. Wong, David Coghill, Tessa Couper, Gabriele Masi, Antonella Gagliano, Marco Lamberti, Dino Maschietto, Antonella Costantino, Paola Morosini, Maria Elisa Fazzi, Klaus-Ulrich Oehler, Martina Pitzer, Jörg Fegert, Frank Häßler, Tobias Renner, Fabian Härtling, Marcel Romanos, Adam Alfred, Veit Roessner, Susanne Wallitza, Henrik Uebel-von Sandersleben
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Summary:Methylphenidate is the most frequently prescribed medication for the treatment of ADHD in children and adolescents in many countries. Although many randomised controlled trials support short-term efficacy, tolerability, and safety, data on long-term safety and tolerability are scarce. The aim of this study was to investigate the safety of methylphenidate over a 2-year period in relation to growth and development, psychiatric health, neurological health, and cardiovascular function in children and adolescents.
Item Description:Online veröffentlicht am 20. März 2023
Gesehen am 20.12.2023
Physical Description:Online Resource
ISSN:2215-0374
DOI:10.1016/S2215-0366(23)00042-1

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