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Effects of inosine on reperfusion injury after cardiopulmonary bypass

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Inosine, a break-down product of adenosine has been recently shown to exert inodilatory and anti-inflammatory properties. Furthermore inosine might be a key substrate of pharmacological post-conditioning. In the present pre-clinical study, we investigated the effects of inosine on cardiac function d...

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Bibliographic Details
Main Authors: Veres, Gábor (Author) , Radovits, Tamás (Author) , Seres, Leila (Author) , Horkay, Ferenc (Author) , Karck, Matthias (Author) , Szabó, Gábor (Author)
Format: Article (Journal)
Language:English
Published: 8 November 2010
In: Journal of cardiothoracic surgery
Year: 2010, Volume: 5, Pages: 1-6
ISSN:1749-8090
DOI:10.1186/1749-8090-5-106
Online Access:Resolving-System, kostenfrei, Volltext: https://doi.org/10.1186/1749-8090-5-106
Verlag, kostenfrei, Volltext: https://cardiothoracicsurgery.biomedcentral.com/articles/10.1186/1749-8090-5-106
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Author Notes:Gábor Veres, Tamás Radovits, Leila Seres, Ferenc Horkay, Matthias Karck, Gábor Szabó
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Summary:Inosine, a break-down product of adenosine has been recently shown to exert inodilatory and anti-inflammatory properties. Furthermore inosine might be a key substrate of pharmacological post-conditioning. In the present pre-clinical study, we investigated the effects of inosine on cardiac function during reperfusion in an experimental model of cardioplegic arrest and extracorporal circulation.
Item Description:Gesehen am 05.09.2023
Physical Description:Online Resource
ISSN:1749-8090
DOI:10.1186/1749-8090-5-106

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