Cross-linking affects cellular condensation and chondrogenesis in type II collagen-GAG scaffolds seeded with bone marrow-derived mesenchymal stem cells
The formation of cartilaginous tissue by chondroprogenitor cells, whether in vivo or in vitro, appears to require a critical initial stage of “condensation” in which intercellular space is reduced through an aggregation of cells, leading to development of cell-to-cell junctions followed by chondrocy...
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| Main Authors: | , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
11 March 2010
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| In: |
Journal of orthopaedic research
Year: 2010, Volume: 28, Issue: 9, Pages: 1184-1192 |
| ISSN: | 1554-527X |
| DOI: | 10.1002/jor.21113 |
| Online Access: | Resolving-System, kostenfrei, Volltext: https://doi.org/10.1002/jor.21113 Verlag, kostenfrei, Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1002/jor.21113 
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| Author Notes: | Scott M. Vickers, Tobias Gotterbarm, Myron Spector |
| Summary: | The formation of cartilaginous tissue by chondroprogenitor cells, whether in vivo or in vitro, appears to require a critical initial stage of “condensation” in which intercellular space is reduced through an aggregation of cells, leading to development of cell-to-cell junctions followed by chondrocytic differentiation. The objective of this study was to investigate the association of aggregation (condensation) of mesenchymal stem cell (MSCs) and chondrogenesis in vitro. |
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| Item Description: | Gesehen am 05.09.2023 |
| Physical Description: | Online Resource |
| ISSN: | 1554-527X |
| DOI: | 10.1002/jor.21113 |