Cross-linking affects cellular condensation and chondrogenesis in type II collagen-GAG scaffolds seeded with bone marrow-derived mesenchymal stem cells
The formation of cartilaginous tissue by chondroprogenitor cells, whether in vivo or in vitro, appears to require a critical initial stage of “condensation” in which intercellular space is reduced through an aggregation of cells, leading to development of cell-to-cell junctions followed by chondrocy...
Enregistré dans:
| Auteurs principaux: | , , |
|---|---|
| Format: | Article (Journal) |
| Langue: | anglais |
| Publié: |
11 March 2010
|
| In: |
Journal of orthopaedic research
Year: 2010, Volume: 28, Numéro: 9, Pages: 1184-1192 |
| ISSN: | 1554-527X |
| DOI: | 10.1002/jor.21113 |
| Accès en ligne: | Resolving-System, kostenfrei, Volltext: https://doi.org/10.1002/jor.21113 Verlag, kostenfrei, Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1002/jor.21113 
|
| Notes sur l'auteur: | Scott M. Vickers, Tobias Gotterbarm, Myron Spector |
| Résumé: | The formation of cartilaginous tissue by chondroprogenitor cells, whether in vivo or in vitro, appears to require a critical initial stage of “condensation” in which intercellular space is reduced through an aggregation of cells, leading to development of cell-to-cell junctions followed by chondrocytic differentiation. The objective of this study was to investigate the association of aggregation (condensation) of mesenchymal stem cell (MSCs) and chondrogenesis in vitro. |
|---|---|
| Description: | Gesehen am 05.09.2023 |
| Description matérielle: | Online Resource |
| ISSN: | 1554-527X |
| DOI: | 10.1002/jor.21113 |