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Biomechanische Analyse von tomografisch unauffälligen Keratokonus-Partneraugen mit dem Corvis ST = Biomechanical analysis of tomographically regular keratoconus fellow eyes using Corvis ST

BACKGROUND: Keratoconus is a bilateral, yet asymmetric disease. In rare cases, the second eye may show no signs of tomographic changes. The purpose of this study was to analyze the biomechanical characteristics in tomographically regular keratoconus fellow eyes. MATERIALS AND METHODS: This retrospec...

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Main Authors: Augustin, Victor A. (Author) , Son, Hyeck Soo (Author) , Kovalchuk, Bogdana (Author) , Yildirim, Timur Mert (Author) , Köppe, Maximilian (Author) , Auffarth, Gerd U. (Author) , Khoramnia, Ramin (Author)
Format: Article (Journal)
Language:German
Published: 2023
In: Klinische Monatsblätter für Augenheilkunde
Year: 2023, Volume: 240, Issue: 8, Pages: 944-951
ISSN:1439-3999
DOI:10.1055/a-2130-7503
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1055/a-2130-7503
Verlag, lizenzpflichtig, Volltext: http://www.thieme-connect.de/DOI/DOI?10.1055/a-2130-7503
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Author Notes:Victor A. Augustin, Hyeck-Soo Son, Bogdana Kovalchuk, Timur Mert Yildirim, Maximilian K. Köppe, Gerd U. Auffarth, Ramin Khoramnia
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Summary:BACKGROUND: Keratoconus is a bilateral, yet asymmetric disease. In rare cases, the second eye may show no signs of tomographic changes. The purpose of this study was to analyze the biomechanical characteristics in tomographically regular keratoconus fellow eyes. MATERIALS AND METHODS: This retrospective, consecutive case series analyzed 916 eyes of 458 patients who presented to our keratoconus clinic between November 2020 and October 2022. Primary outcome measures included best-corrected visual acuity (BCVA), tomographic Scheimpflug analysis using Pentacam AXL (Oculus, Wetzlar, Germany), and biomechanical assessment using Corvis ST (Oculus, Wetzlar, Germany). Tomographic changes were assessed via analysis of the anterior and posterior curvature, K-max, thinnest corneal thickness (TCT), the Belin/Ambrosio Deviation Display (BAD-D), and the ABCD-Grading. Biomechanical changes were analyzed using Corvis Biomechanical Index (CBI) and Tomographic Biomechanical Index (TBI). RESULTS: Of 916 eyes, 34 tomographically regular fellow eyes (7.4%) were identified and included in the analysis. Overall, the mean BCVA was - 0.02 ± 0.13 logMAR. Tomographic analysis showed mean K-max of 43.87 ± 1.21 D, mean TCT of 532 ± 23 µm, and mean BAD-D of 1.02 ± 0.43. Biomechanical analysis demonstrated mean CBI of 0.28 ± 0.26 and mean TBI of 0.34 ± 0.30. While normal CBI-values were observed in 16 (47%) of 34 eyes, only 13 eyes (38%) showed a regular TBI and only 7 eyes (21%) showed regular TBI and CBI. The sensitivity of CBI and TBI to detect a tomographically normal keratoconus fellow eye was 53% and 62%, respectively. CONCLUSION: A highly asymmetric corneal ectasia with regular tomographic finding in a fellow eye is rare among keratoconus patients. In such cases, a biomechanical analysis may be useful in detecting early signs of corneal ectasia. In our analysis, the TBI showed high sensitivity for detecting a biomechanical abnormality in tomographically regular fellow eyes.
Item Description:Artikel online veröffentlicht: 11. August 2023
Gesehen am 08.09.2023
Physical Description:Online Resource
ISSN:1439-3999
DOI:10.1055/a-2130-7503

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