68Ga-FAPI-PET/CT in patients with various gynecological malignancies

Purpose 68Ga-FAPI (fibroblast activation protein inhibitor) is a novel and highly promising radiotracer for PET/CT imaging. The aim of this retrospective analysis is to explore the potential of FAPI-PET/CT in gynecological malignancies. We asse ssed biodistribution, tumor uptake, and the influence o...

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Main Authors: Dendl, Katharina (Author) , Körber, Stefan A. (Author) , Finck, Rebecca (Author) , Mokoala, Kgomotso M. G. (Author) , Staudinger, Fabian (Author) , Schillings, Lisa (Author) , Heger, Ulrike (Author) , Röhrich, Manuel (Author) , Kratochwil, Clemens (Author) , Sathekge, Mike (Author) , Jäger, Dirk (Author) , Debus, Jürgen (Author) , Haberkorn, Uwe (Author) , Giesel, Frederik L. (Author)
Format: Article (Journal)
Language:English
Published: 29 May 2021
In: European journal of nuclear medicine and molecular imaging
Year: 2021, Volume: 48, Issue: 12, Pages: 4089-4100
ISSN:1619-7089
DOI:10.1007/s00259-021-05378-0
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1007/s00259-021-05378-0
Verlag, kostenfrei, Volltext: https://link.springer.com/10.1007/s00259-021-05378-0
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Author Notes:Katharina Dendl, Stefan A. Koerber, Rebecca Finck, Kgomotso M.G. Mokoala, Fabian Staudinger, Lisa Schillings, Ulrike Heger, Manuel Röhrich, Clemens Kratochwil, Mike Sathekge, Dirk Jäger, Jürgen Debus, Uwe Haberkorn, Frederik L. Giesel
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Summary:Purpose 68Ga-FAPI (fibroblast activation protein inhibitor) is a novel and highly promising radiotracer for PET/CT imaging. The aim of this retrospective analysis is to explore the potential of FAPI-PET/CT in gynecological malignancies. We asse ssed biodistribution, tumor uptake, and the influence of pre- or postmenopausal status on tracer accumulation in hormone-sensitive organs. Furthermore, a comparison with the current standard oncological tracer 18F-FDG was performed in selected cases.
Item Description:Im Titel ist "68" hochgestellt
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Physical Description:Online Resource
ISSN:1619-7089
DOI:10.1007/s00259-021-05378-0