The role of HMGB1/RAGE in inflammatory cardiomyopathy
We propose that the interaction of HMGB1 and RAGE is a key component initiating and sustaining the inflammatory response in inflammatory cardiomyopathy eventually leading to heart failure. Thus HMGB1-antagonizing gene therapy represents a new therapeutic strategy...
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| Hauptverfasser: | , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
22. April 2010
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| In: |
Seminars in thrombosis and hemostasis
Year: 2010, Jahrgang: 36, Heft: 2, Pages: 185-194 |
| ISSN: | 1098-9064 |
| DOI: | 10.1055/s-0030-1251503 |
| Online-Zugang: | Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1055/s-0030-1251503 Verlag, lizenzpflichtig, Volltext: https://www.thieme-connect.de/products/ejournals/abstract/10.1055/s-0030-1251503 |
| Verfasserangaben: | Hans C. Volz, Ziya Kaya, Hugo A. Katus, and Martin Andrassy |
| Zusammenfassung: | We propose that the interaction of HMGB1 and RAGE is a key component initiating and sustaining the inflammatory response in inflammatory cardiomyopathy eventually leading to heart failure. Thus HMGB1-antagonizing gene therapy represents a new therapeutic strategy... |
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| Beschreibung: | Gesehen am 13.09.2023 |
| Beschreibung: | Online Resource |
| ISSN: | 1098-9064 |
| DOI: | 10.1055/s-0030-1251503 |