The role of HMGB1/RAGE in inflammatory cardiomyopathy
We propose that the interaction of HMGB1 and RAGE is a key component initiating and sustaining the inflammatory response in inflammatory cardiomyopathy eventually leading to heart failure. Thus HMGB1-antagonizing gene therapy represents a new therapeutic strategy...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
22. April 2010
|
| In: |
Seminars in thrombosis and hemostasis
Year: 2010, Volume: 36, Issue: 2, Pages: 185-194 |
| ISSN: | 1098-9064 |
| DOI: | 10.1055/s-0030-1251503 |
| Online Access: | Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1055/s-0030-1251503 Verlag, lizenzpflichtig, Volltext: https://www.thieme-connect.de/products/ejournals/abstract/10.1055/s-0030-1251503 |
| Author Notes: | Hans C. Volz, Ziya Kaya, Hugo A. Katus, and Martin Andrassy |
| Summary: | We propose that the interaction of HMGB1 and RAGE is a key component initiating and sustaining the inflammatory response in inflammatory cardiomyopathy eventually leading to heart failure. Thus HMGB1-antagonizing gene therapy represents a new therapeutic strategy... |
|---|---|
| Item Description: | Gesehen am 13.09.2023 |
| Physical Description: | Online Resource |
| ISSN: | 1098-9064 |
| DOI: | 10.1055/s-0030-1251503 |