The role of HMGB1/RAGE in inflammatory cardiomyopathy

We propose that the interaction of HMGB1 and RAGE is a key component initiating and sustaining the inflammatory response in inflammatory cardiomyopathy eventually leading to heart failure. Thus HMGB1-antagonizing gene therapy represents a new therapeutic strategy...

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Bibliographic Details
Main Authors: Volz, Hans Christian (Author) , Kaya, Ziya (Author) , Katus, Hugo (Author) , Andrassy, Martin (Author)
Format: Article (Journal)
Language:English
Published: 22. April 2010
In: Seminars in thrombosis and hemostasis
Year: 2010, Volume: 36, Issue: 2, Pages: 185-194
ISSN:1098-9064
DOI:10.1055/s-0030-1251503
Online Access:Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1055/s-0030-1251503
Verlag, lizenzpflichtig, Volltext: https://www.thieme-connect.de/products/ejournals/abstract/10.1055/s-0030-1251503
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Author Notes:Hans C. Volz, Ziya Kaya, Hugo A. Katus, and Martin Andrassy
Description
Summary:We propose that the interaction of HMGB1 and RAGE is a key component initiating and sustaining the inflammatory response in inflammatory cardiomyopathy eventually leading to heart failure. Thus HMGB1-antagonizing gene therapy represents a new therapeutic strategy...
Item Description:Gesehen am 13.09.2023
Physical Description:Online Resource
ISSN:1098-9064
DOI:10.1055/s-0030-1251503