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Reduced immune effector cell NKG2D expression and increased levels of soluble NKG2D ligands in multiple myeloma may not be causally linked

There is limited understanding of the dysregulation of the innate immune system in multiple myeloma (MM). We analysed the expression of the activating receptor NKG2D on NK cells and T cells of MM patients and investigated the impact of soluble versus membrane-bound NKG2D ligands on the expression of...

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Main Authors: Lilienfeld-Toal, Marie von (Author) , Frank, Susanne (Author) , Leyendecker, Christiane (Author) , Feyler, Sylvia (Author) , Jarmin, Sarah (Author) , Morgan, Ruth (Author) , Glasmacher, Axel (Author) , Märten, Angela (Author) , Schmidt-Wolf, Ingo G. H. (Author) , Brossart, Peter (Author) , Cook, Gordon (Author)
Format: Article (Journal)
Language:English
Published: 2010
In: Cancer immunology immunotherapy
Year: 2010, Volume: 59, Issue: 6, Pages: 829-839
ISSN:1432-0851
DOI:10.1007/s00262-009-0807-3
Online Access:Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1007/s00262-009-0807-3
Verlag, lizenzpflichtig, Volltext: https://link.springer.com/article/10.1007/s00262-009-0807-3
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Author Notes:Marie von Lilienfeld-Toal, Susanne Frank, Christiane Leyendecker, Sylvia Feyler, Sarah Jarmin, Ruth Morgan, Axel Glasmacher, Angela Märten, Ingo G.H. Schmidt-Wolf, Peter Brossart, Gordon Cook

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