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Comparison of CT, MRI, and F-18 FDG PET/CT for initial N-staging of oral squamous cell carcinoma: a cost-effectiveness analysis

Treatment of oral squamous cell carcinoma (OSCC) is based on clinical exam, biopsy, and a precise imaging-based TNM-evaluation. A high sensitivity and specificity for magnetic resonance imaging (MRI) and F-18 FDG PET/CT are reported for N-staging. Nevertheless, staging of oral squamous cell carcinom...

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Main Authors: Burian, Egon (Author) , Palla, Benjamin (Author) , Callahan, Nicholas (Author) , Pyka, Thomas (Author) , Wolff, Constantin (Author) , von Schacky, Claudio E. (Author) , Schmid, Annabelle (Author) , Froelich, Matthias F. (Author) , Rübenthaler, Johannes (Author) , Makowski, Marcus R. (Author) , Gassert, Felix (Author)
Format: Article (Journal)
Language:English
Published: 24 May 2022
In: European journal of nuclear medicine and molecular imaging
Year: 2022, Volume: 49, Issue: 11, Pages: 3870-3877
ISSN:1619-7089
DOI:10.1007/s00259-022-05843-4
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1007/s00259-022-05843-4
Verlag, kostenfrei, Volltext: https://link.springer.com/article/10.1007/s00259-022-05843-4
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Author Notes:Egon Burian, Benjamin Palla, Nicholas Callahan, Thomas Pyka, Constantin Wolff, Claudio E. von Schacky, Annabelle Schmid, Matthias F. Froelich, Johannes Rübenthaler, Marcus R. Makowski, Felix G. Gassert
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Summary:Treatment of oral squamous cell carcinoma (OSCC) is based on clinical exam, biopsy, and a precise imaging-based TNM-evaluation. A high sensitivity and specificity for magnetic resonance imaging (MRI) and F-18 FDG PET/CT are reported for N-staging. Nevertheless, staging of oral squamous cell carcinoma is most often based on computed tomography (CT) scans. This study aims to evaluate cost-effectiveness of MRI and PET/CT compared to standard of care imaging in initial staging of OSCC within the US Healthcare System.
Item Description:Gesehen am 18.09.2023
Physical Description:Online Resource
ISSN:1619-7089
DOI:10.1007/s00259-022-05843-4

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