Infiltrative growth pattern of prostate cancer is associated with lower uptake on PSMA PET and reduced diffusion restriction on mpMRI

Recently, a significant association was shown between novel growth patterns on histopathology of prostate cancer (PCa) and prostate-specific membrane antigen (PSMA) uptake on [68Ga]PSMA-PET. It is the aim of this study to evaluate the association between these growth patterns and ADC (mm2/1000 s) va...

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Main Authors: Laudicella, Riccardo (Author) , Rüschoff, Jan H. (Author) , Ferraro, Daniela A. (Author) , Brada, Muriel D. (Author) , Hausmann, Daniel (Author) , Mebert, Iliana (Author) , Maurer, Alexander (Author) , Hermanns, Thomas (Author) , Eberli, Daniel (Author) , Rupp, Niels J. (Author) , Burger, Irene A. (Author)
Format: Article (Journal)
Language:English
Published: 18 April 2022
In: European journal of nuclear medicine and molecular imaging
Year: 2022, Volume: 49, Issue: 11, Pages: 3917-3928
ISSN:1619-7089
DOI:10.1007/s00259-022-05787-9
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1007/s00259-022-05787-9
Verlag, kostenfrei, Volltext: https://link.springer.com/article/10.1007/s00259-022-05787-9
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Author Notes:Riccardo Laudicella, Jan H. Rüschoff, Daniela A. Ferraro, Muriel D. Brada, Daniel Hausmann, Iliana Mebert, Alexander Maurer, Thomas Hermanns, Daniel Eberli, Niels J. Rupp, Irene A. Burger
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Summary:Recently, a significant association was shown between novel growth patterns on histopathology of prostate cancer (PCa) and prostate-specific membrane antigen (PSMA) uptake on [68Ga]PSMA-PET. It is the aim of this study to evaluate the association between these growth patterns and ADC (mm2/1000 s) values in comparison to [68Ga]PSMA uptake on PET/MRI.
Item Description:Gesehen am 26.09.2023
Physical Description:Online Resource
ISSN:1619-7089
DOI:10.1007/s00259-022-05787-9