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Multiple effects of silymarin on the hepatitis C virus lifecycle

Silymarin, an extract from milk thistle (Silybum marianum), and its purified flavonolignans have been recently shown to inhibit hepatitis C virus (HCV) infection, both in vitro and in vivo. In the current study, we further characterized silymarin's antiviral actions. ...

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Bibliographic Details
Main Authors: Wagoner, Jessica (Author) , Negash, Amina (Author) , Kane, Olivia J. (Author) , Martinez, Laura E. (Author) , Nahmias, Yaakov (Author) , Bourne, Nigel (Author) , Owen, David M. (Author) , Grove, Joe (Author) , Brimacombe, Claire (Author) , McKeating, Jane A. (Author) , Pécheur, Eve-Isabelle (Author) , Graf, Tyler N. (Author) , Oberlies, Nicholas H. (Author) , Lohmann, Volker (Author) , Cao, Feng (Author) , Tavis, John E. (Author) , Polyak, Stephen J. (Author)
Format: Article (Journal)
Language:English
Published: 23 May 2010
In: Hepatology
Year: 2010, Volume: 51, Issue: 6, Pages: 1912-1921
ISSN:1527-3350
DOI:10.1002/hep.23587
Online Access:Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1002/hep.23587
Verlag, lizenzpflichtig, Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1002/hep.23587
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Author Notes:Jessica Wagoner, Amina Negash, Olivia J. Kane, Laura E. Martinez, Yaakov Nahmias, Nigel Bourne, David M. Owen, Joe Grove, Claire Brimacombe, Jane A. McKeating, Eve-Isabelle Pécheur, Tyler N. Graf, Nicholas H. Oberlies, Volker Lohmann, Feng Cao, John E. Tavis, and Stephen J. Polyak
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Summary:Silymarin, an extract from milk thistle (Silybum marianum), and its purified flavonolignans have been recently shown to inhibit hepatitis C virus (HCV) infection, both in vitro and in vivo. In the current study, we further characterized silymarin's antiviral actions. ...
Item Description:Gesehen am 28.09.2023
Physical Description:Online Resource
ISSN:1527-3350
DOI:10.1002/hep.23587

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